PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28597291-8 2017 The accumulation of sulpiride in primary human trophoblast cells was obviously affected by inhibitors of OCT3, OCTN1 and OCTN2. Sulpiride 20-29 solute carrier family 22 member 4 Homo sapiens 111-116 28597291-9 2017 The above results indicate that hOCTN1 and hOCTN2 likely contribute to the sulpiride uptake from maternal circulation to trophoblast cells, while hMDR1 and hBCRP mediate the efflux from trophoblast cells to maternal circulation, and hOCT3 probably is involved in the bidirectional transport of sulpiride between the placenta and fetal blood. Sulpiride 75-84 solute carrier family 22 member 4 Homo sapiens 32-38 28926871-7 2017 The results implied that OCTN1, OCTN2, OCT2, MATE1 and MATE2-K probably contributed to the renal transfer of sulpiride, in which OCT2 mediated the uptake of sulpiride from the bloodstream to the proximal tubular cells, while MATEs contributed to the sulpiride efflux from the proximal tubular cells to the renal lumen, and OCTNs participated in both renal secretion and reabsorption. Sulpiride 109-118 solute carrier family 22 member 4 Homo sapiens 25-30 12392092-6 2002 The results obtained from these examinations indicated that the apical-to-basolateral transport of sulpiride is mediated by the peptide transporter PEPT1, organic cation transporters OCTN1 and OCTN2 on the apical membrane, and the basolateral peptide transporter on the basolateral membrane. Sulpiride 99-108 solute carrier family 22 member 4 Homo sapiens 183-188 12392092-8 2002 A decrease in the absorption of sulpiride may occur in coadministration protocols involving PEPT1-, OCTN1-, and OCTN2-transported drugs. Sulpiride 32-41 solute carrier family 22 member 4 Homo sapiens 100-105 28926871-4 2017 The results demonstrated that sulpiride was a substrate of human carnitine/organic cation transporter 1 (hOCTN1) and 2 (hOCTN2), human organic cation transporter 2 (hOCT2), human multidrug and toxin efflux extrusion protein 1 (hMATE1) and 2-K (hMATE2-K). Sulpiride 30-39 solute carrier family 22 member 4 Homo sapiens 105-111 25155823-5 2014 We then studied the uptake of amisulpride and sulpiride by the organic cation transporters of the SLC22 family OCT1, OCT2, OCT3, OCTN1, and OCTN2 Amisulpride was found to be transported by all five transporters studied. Sulpiride 46-55 solute carrier family 22 member 4 Homo sapiens 129-134