PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9257124-1	1997	This study uses microsomal membranes from rat testis tissue, including the cytochrome P450c17 (steroid 17 alpha-monooxygenase/17 alpha-hydroxyprogesterone aldolase, catalyzing the conversion of progesterone to androstenedione), to decipher the possible relation of NADPH-induced (no exogenous iron added) lipid peroxidation and cytochrome P450 inactivation and the protective effect of certain steroids.	Androstenedione	210-225	cytochrome P450, family 17, subfamily a, polypeptide 1	Rattus norvegicus	75-93	
11514054-7	2001	This inhibitory effect was abolished by androstendione, suggesting that P450c17 was suppressed by IL-1.	Androstenedione	40-54	cytochrome P450, family 17, subfamily a, polypeptide 1	Rattus norvegicus	72-79	
24451217-6	2014	The CYP17A1 enzyme is critical for androgen biosynthesis and catalyzes conversion of progesterone into androstenedione.	Androstenedione	103-118	cytochrome P450, family 17, subfamily a, polypeptide 1	Rattus norvegicus	4-11	
9029727-1	1997	Studies of the regulation of androgen synthesis in steroidogenic cells have focused on both transcriptional and post-translational regulation of the proteins that catalyze these reactions: the P450c17 that catalyzes the production of DHEA or androstenedione in consecutive hydroxylase and lyase activities, and the 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) that catalyzes the conversion of androstenedione to testosterone.	Androstenedione	242-257	cytochrome P450, family 17, subfamily a, polypeptide 1	Rattus norvegicus	193-200	
9029727-1	1997	Studies of the regulation of androgen synthesis in steroidogenic cells have focused on both transcriptional and post-translational regulation of the proteins that catalyze these reactions: the P450c17 that catalyzes the production of DHEA or androstenedione in consecutive hydroxylase and lyase activities, and the 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) that catalyzes the conversion of androstenedione to testosterone.	Androstenedione	399-414	cytochrome P450, family 17, subfamily a, polypeptide 1	Rattus norvegicus	193-200	
22800812-2	2012	However, the presence of the cytochrome P450 17alpha-hydroxylase/C(17,20)-lyase (P450C(17)), an enzyme that converts pregnenolone and progesterone into dehydroepiandrosterone and androstenedione, in specific areas of the cerebellum such as the deep cerebellar nuclei, remains virtually unexplored.	Androstenedione	179-194	cytochrome P450, family 17, subfamily a, polypeptide 1	Rattus norvegicus	86-90	
22087261-6	2011	Thus, the hormone data suggested that steroidogenesis was blocked at the level of the 17,20 lyase activity of the P450c17 enzyme (CYP17), converting 17alpha-OHP to androstenedione.	Androstenedione	164-179	cytochrome P450, family 17, subfamily a, polypeptide 1	Rattus norvegicus	130-135