PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16467117-2	2006	MCF-7/CA cells overexpressing HER-2 showed a >2-fold increase in estrogen receptor (ER)-mediated transcriptional reporter activity upon treatment with androstenedione compared with vector-only control MCF-7/CA cells.	Androstenedione	154-169	estrogen receptor 1	Homo sapiens	68-85	
22550166-6	2012	In a cell line model of resistance to letrozole (LetR), we found ERalpha/AIB1 promoter recruitment and subsequent expression of the classic ER target genes pS2 and Myc to be constitutively upregulated in the presence of both androstenedione and letrozole.	Androstenedione	225-240	estrogen receptor 1	Homo sapiens	65-72	
19435899-4	2009	As expected in this system, estrogen (E2) or androstenedione induced a proliferative response and increased ER-mediated transcription in ER-positive cell lines expressing aromatase.	Androstenedione	45-60	estrogen receptor 1	Homo sapiens	108-110	
19435899-4	2009	As expected in this system, estrogen (E2) or androstenedione induced a proliferative response and increased ER-mediated transcription in ER-positive cell lines expressing aromatase.	Androstenedione	45-60	estrogen receptor 1	Homo sapiens	137-139	
19435899-5	2009	However, surprisingly, in the presence of androstenedione, PTK/ZK suppressed both the androstenedione-stimulated proliferation and ER-mediated transcription.	Androstenedione	42-57	estrogen receptor 1	Homo sapiens	131-133	
17158782-4	2007	Late-stage ER alpha-null follicles exhibited markedly increased expression of the thecal cell enzyme CYP17A1 and secreted much greater amounts of its end product, androstenedione.	Androstenedione	163-178	estrogen receptor 1	Homo sapiens	11-19	
16467117-2	2006	MCF-7/CA cells overexpressing HER-2 showed a >2-fold increase in estrogen receptor (ER)-mediated transcriptional reporter activity upon treatment with androstenedione compared with vector-only control MCF-7/CA cells.	Androstenedione	154-169	estrogen receptor 1	Homo sapiens	31-33	
12231116-0	2002	The estrogen receptor alpha gene determines serum androstenedione levels in postmenopausal women.	Androstenedione	50-65	estrogen receptor 1	Homo sapiens	4-27	
12231116-2	2002	The purpose of this study was to assess the association between the estrogen receptor (ER) alpha gene polymorphisms XbaI and PvuII and circulating levels of androstenedione, a precursor of sex-steroids synthetized in the ovary and adrenal.	Androstenedione	157-172	estrogen receptor 1	Homo sapiens	68-96	
32019227-5	2020	Increased production of estradiol and mRNA expression of ERalpha (ESR1) were observed in androstenedione-induced COV434 granulosa cells treated with the CO + RF extract.	Androstenedione	89-104	estrogen receptor 1	Homo sapiens	57-64	
32019227-5	2020	Increased production of estradiol and mRNA expression of ERalpha (ESR1) were observed in androstenedione-induced COV434 granulosa cells treated with the CO + RF extract.	Androstenedione	89-104	estrogen receptor 1	Homo sapiens	66-70