PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25664020-0 2014 The cyclic AMP response element-binding protein antisense oligonucleotide induced anti-nociception and decreased the expression of KIF17 in spinal cord after peripheral nerve injury in mice. Oligonucleotides 58-73 cAMP responsive element binding protein 1 Mus musculus 4-47 25664020-4 2014 This study is to investigate the role and mechanism of CREB antisense oligonucleotide (ODN) in neuropathic pain induced by chronic constriction injury (CCI) in mice. Oligonucleotides 70-85 cAMP responsive element binding protein 1 Mus musculus 55-59 25664020-5 2014 RESULTS: CCI surgery decreased thresholds of mechanical allodynia and thermal hyperalgesia whereas CREB antisense oligonucleotide ODN significantly attenuated these pain behaviors (P < 0.05). Oligonucleotides 114-129 cAMP responsive element binding protein 1 Mus musculus 99-103 25664020-9 2014 CONCLUSIONS: CREB antisense oligonucleotide ODN may reduce neuropathic pain through targeting CREB and decreasing the expression of pCREB and KIF17. Oligonucleotides 28-43 cAMP responsive element binding protein 1 Mus musculus 13-17 25664020-9 2014 CONCLUSIONS: CREB antisense oligonucleotide ODN may reduce neuropathic pain through targeting CREB and decreasing the expression of pCREB and KIF17. Oligonucleotides 28-43 cAMP responsive element binding protein 1 Mus musculus 94-98 23633027-7 2013 The increase of NR1 and NR2B subunits of the NMDAR was significantly diminished by intrathecal administration of the CREB antisense oligonucleotide against CREB and pCREB. Oligonucleotides 132-147 cAMP responsive element binding protein 1 Mus musculus 117-121 25573318-6 2014 Compared with saline group, mechanical and thermal hyperalgesia significantly decreased and the expression of p-CREB protein decreased at spinal cord in oligonucleotide group. Oligonucleotides 153-168 cAMP responsive element binding protein 1 Mus musculus 112-116 23633027-7 2013 The increase of NR1 and NR2B subunits of the NMDAR was significantly diminished by intrathecal administration of the CREB antisense oligonucleotide against CREB and pCREB. Oligonucleotides 132-147 cAMP responsive element binding protein 1 Mus musculus 156-160 23633027-8 2013 Additionally, nociceptive behavior induced by CCI was attenuated by intrathecal administration of the CREB antisense oligonucleotide during the period of injection, and the above effects of relieving pain lasted at least 12 days following the last injection. Oligonucleotides 117-132 cAMP responsive element binding protein 1 Mus musculus 102-106 19821778-4 2010 On electrophoretic mobility shift analysis, PTH stimulated binding of phosphorylated CREB to an oligonucleotide spanning the CRE and binding of NFATc1, c-Fos, and c-Jun to an oligonucleotide spanning the NFAT/AP-1 composite site. Oligonucleotides 96-111 cAMP responsive element binding protein 1 Mus musculus 85-89 19282384-6 2009 An oligonucleotide probe containing a CREB/activating transcription factor binding region in the StAR promoter was found to bind nuclear proteins in PMA and (Bu)(2)cAMP-treated MA-10 and KK-1 cells. Oligonucleotides 3-18 cAMP responsive element binding protein 1 Mus musculus 38-42 16164634-11 2005 Binding of phosphorylated CREB to a CREB oligonucleotide was significantly increased after 0.5 mmol/L H(2)O(2) but decreased after 1 mmol/L H(2)O(2). Oligonucleotides 41-56 cAMP responsive element binding protein 1 Mus musculus 26-30 16164634-11 2005 Binding of phosphorylated CREB to a CREB oligonucleotide was significantly increased after 0.5 mmol/L H(2)O(2) but decreased after 1 mmol/L H(2)O(2). Oligonucleotides 41-56 cAMP responsive element binding protein 1 Mus musculus 36-40 11956331-6 2002 Antisense oligonucleotides against CREB, GATA-2 and SOX-5 significantly reduced charge movement in C2C12 cells. Oligonucleotides 10-26 cAMP responsive element binding protein 1 Mus musculus 35-39 12887679-2 2003 We investigated the relationship between CREB and ischemic tolerance in gerbil hippocampal CA1 neurons using CRE decoy oligonucleotide. Oligonucleotides 119-134 cAMP responsive element binding protein 1 Mus musculus 41-45 12887679-5 2003 The administration of CRE decoy oligonucleotide into gerbil cerebral ventricle decreased CREB-DNA binding activity to 38% of the control. Oligonucleotides 32-47 cAMP responsive element binding protein 1 Mus musculus 89-93 12471138-6 2002 Of interest, we detected a significant decrease of NF-kappaB, AP-1, and CREB DNA binding activities by reciprocal competition for these binding sites when either specific cold oligonucleotides (NF-kappaB, AP-1, and CREB) or Abs against various transcription factor subunits (p50, p65, c-Fos, Jun B, c-Jun, and CREB-1) were added. Oligonucleotides 176-192 cAMP responsive element binding protein 1 Mus musculus 72-76 12471138-6 2002 Of interest, we detected a significant decrease of NF-kappaB, AP-1, and CREB DNA binding activities by reciprocal competition for these binding sites when either specific cold oligonucleotides (NF-kappaB, AP-1, and CREB) or Abs against various transcription factor subunits (p50, p65, c-Fos, Jun B, c-Jun, and CREB-1) were added. Oligonucleotides 176-192 cAMP responsive element binding protein 1 Mus musculus 215-219 12471138-6 2002 Of interest, we detected a significant decrease of NF-kappaB, AP-1, and CREB DNA binding activities by reciprocal competition for these binding sites when either specific cold oligonucleotides (NF-kappaB, AP-1, and CREB) or Abs against various transcription factor subunits (p50, p65, c-Fos, Jun B, c-Jun, and CREB-1) were added. Oligonucleotides 176-192 cAMP responsive element binding protein 1 Mus musculus 310-316 15213229-10 2004 We demonstrated that the transcription factors from RINm5F nuclear extracts specifically bound to oligonucleotides containing C/EBP, AhR, or CREB consensus sites. Oligonucleotides 98-114 cAMP responsive element binding protein 1 Mus musculus 141-145 9596555-2 1998 Binding of radiolabeled oligonucleotide probes for the "leucine-zipper" transcription factors, including activator protein-1 (AP1) and cyclic AMP response element binding protein (CREB), was markedly reduced in nuclear extracts of the adrenals from mice sacrificed 2 h after the subcutaneous injection of triamcinolone acetonide (TA), an agonist at glucocorticoid (GC) receptors which are also a transcription factor with "zinc-finger" motifs. Oligonucleotides 24-39 cAMP responsive element binding protein 1 Mus musculus 135-178 11564732-7 2001 Electrophoretic mobility shift assays demonstrated that transcription factors CREB/CREM and USF1/USF2 in As4.1 cell nuclear extracts bind to oligonucleotides containing the Ren-1(c) CRE and E-box, respectively. Oligonucleotides 141-157 cAMP responsive element binding protein 1 Mus musculus 78-82 11108134-8 2000 To verify gene induction by cAMP in association with protection we established activation of cAMP response element binding protein (CREB) by gel-shift analysis and moreover, treated macrophages with oligonucleotides containing a cAMP-responsive element (CRE) in order to scavenge CREB. Oligonucleotides 199-215 cAMP responsive element binding protein 1 Mus musculus 280-284 9596555-2 1998 Binding of radiolabeled oligonucleotide probes for the "leucine-zipper" transcription factors, including activator protein-1 (AP1) and cyclic AMP response element binding protein (CREB), was markedly reduced in nuclear extracts of the adrenals from mice sacrificed 2 h after the subcutaneous injection of triamcinolone acetonide (TA), an agonist at glucocorticoid (GC) receptors which are also a transcription factor with "zinc-finger" motifs. Oligonucleotides 24-39 cAMP responsive element binding protein 1 Mus musculus 180-184 7615829-7 1995 In AtT20 cells, electrophoretic mobility shift assays and factor-specific antibody supershifts showed that an oligonucleotide containing the chromogranin A CRE site formed a single, homogeneous protein-DNA complex containing the CRE-binding protein CREB. Oligonucleotides 110-125 cAMP responsive element binding protein 1 Mus musculus 249-253 9549403-5 1997 In aplysia, CREB activation has been interfered with by microinjection of CRE containing oligonucleotides into cultured neurons. Oligonucleotides 89-105 cAMP responsive element binding protein 1 Mus musculus 12-16 8683108-6 1996 Binding activity was competed with unlabeled oligonucleotides that contained the junB CRE-like site or the somatostatin CRE consensus motif, the latter observation suggests that members of the activating transcription factor/CRE binding protein (CREB) family may mediate mIg-dependent junB transcription. Oligonucleotides 45-61 cAMP responsive element binding protein 1 Mus musculus 246-250 8885292-1 1996 Nuclear extracts of mouse brain contained binding of radiolabeled oligonucleotide probes for particular transcription factors with leucine-zipper motifs including activator protein-1 (AP1), cyclic AMP response element binding protein (CREB) and c-Myc. Oligonucleotides 66-81 cAMP responsive element binding protein 1 Mus musculus 190-233 34819637-8 2022 injection of CREB-DNA/RNA heteroduplex oligonucleotides (CREB-HDO) or BDNF exon IV-HDO blocked the antidepressant-like effects of (R)-ketamine in CSDS susceptible mice. Oligonucleotides 39-55 cAMP responsive element binding protein 1 Mus musculus 57-61