PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16990616-0 2007 Anti-inflammatory activity of inhaled IL-4 receptor-alpha antisense oligonucleotide in mice. Oligonucleotides 68-83 interleukin 4 Mus musculus 38-42 11241672-8 2001 Furthermore, an oligonucleotide which includes the two STAT recognition sites residing in the IL-4 responsive region of the beta(3) promoter, competes for STAT-6 binding. Oligonucleotides 16-31 interleukin 4 Mus musculus 94-98 15584925-3 2004 We identified an interleukin-4-responsive element at nt -671 on the murine gene promoter, to which the transcription factor STAT6 binds, as shown by reporter gene analysis and STAT6/DNA interaction studies in living cells with transcription factor decoy oligonucleotides. Oligonucleotides 254-270 interleukin 4 Mus musculus 17-30 14500660-5 2003 In the present study, novel IL-4- and Stat6-regulated genes were discovered by using Stat6(-/-) mice and Affymetrix oligonucleotide arrays. Oligonucleotides 116-131 interleukin 4 Mus musculus 28-32 12085000-10 2002 RESULTS: Treatment with anti-MD-1 oligonucleotides or antibodies suppressed rejection of both xeno- and allogeneic grafts, decreased induction of graft-specific cytotoxic T cells, increased production of type-2 cytokines (IL-4 and IL-10), and decreased production of type-1 cytokines (IL-2 and interferon-gamma). Oligonucleotides 34-50 interleukin 4 Mus musculus 222-226 11207258-7 2001 The inhibitory effect of IL-4 was paralleled by nuclear translocation of STAT6, which in EMSAs was able to bind to the same DNA oligonucleotide as STAT4. Oligonucleotides 128-143 interleukin 4 Mus musculus 25-29 8757301-6 1996 After stimulation of naive lymphoid cells with IL-4, sIL-4R release was dependent on up-regulation of spliced IL-4R mRNA, as shown by inhibition with specific antisense oligonucleotides. Oligonucleotides 169-185 interleukin 4 Mus musculus 47-51 10950124-6 2000 Topical administration of IL-4 on experimental wounds in mice significantly accelerated the rate of healing, whereas IL-4 antisense oligonucleotides significantly inhibited healing. Oligonucleotides 132-148 interleukin 4 Mus musculus 117-121 11872954-0 2001 Oligonucleotide fishing for STAT6: cross-talk between IL-4 and chemokines. Oligonucleotides 0-15 interleukin 4 Mus musculus 54-58 11872954-3 2001 We took advantage of double-stranded oligonucleotide probes containing a STAT6-binding gene-sequence from the promotor of the immunoglobulin heavy chain germline epsilon transcript to study the IL-4-induced DNA binding of STAT6. Oligonucleotides 37-52 interleukin 4 Mus musculus 194-198 8449214-3 1993 Three antisense oligonucleotides (15 and 20 nucleotides) were selected near the ATG initiation codon of the murine IL-4 gene. Oligonucleotides 16-32 interleukin 4 Mus musculus 115-119 7539043-3 1995 Although results of previous experiments had suggested that IL-4 does not phosphorylate or activate the Raf-1 kinase, c-raf antisense oligonucleotides inhibited IL-4-induced proliferation of both myeloid and T cell lines, and IL-4 activated Raf-1 kinase activity in an IL-4-dependent myeloid cell line. Oligonucleotides 134-150 interleukin 4 Mus musculus 161-165 7539043-3 1995 Although results of previous experiments had suggested that IL-4 does not phosphorylate or activate the Raf-1 kinase, c-raf antisense oligonucleotides inhibited IL-4-induced proliferation of both myeloid and T cell lines, and IL-4 activated Raf-1 kinase activity in an IL-4-dependent myeloid cell line. Oligonucleotides 134-150 interleukin 4 Mus musculus 161-165 7539043-3 1995 Although results of previous experiments had suggested that IL-4 does not phosphorylate or activate the Raf-1 kinase, c-raf antisense oligonucleotides inhibited IL-4-induced proliferation of both myeloid and T cell lines, and IL-4 activated Raf-1 kinase activity in an IL-4-dependent myeloid cell line. Oligonucleotides 134-150 interleukin 4 Mus musculus 161-165 7751023-5 1995 In particular, treatment of immune lymph node cells with antisense oligonucleotide to IL-4 inhibited the systemic transfer of CS. Oligonucleotides 67-82 interleukin 4 Mus musculus 86-90 7511679-8 1994 We also found that treatment with the antisense BSAP oligonucleotide downregulated Ig class switching induced by interleukin 4 plus LPS. Oligonucleotides 53-68 interleukin 4 Mus musculus 113-126 1918969-13 1991 Oligonucleotides representing protein binding sites of the IL-4 and LPS-induced DNA-binding proteins cross-compete for protein binding. Oligonucleotides 0-16 interleukin 4 Mus musculus 59-63 2974066-5 1988 We have used synthetic oligonucleotides complementary to the 5" end of mouse IL-2 and IL-4 to specifically block the biosynthesis of IL-2 or IL-4 in two murine helper T cell clones from the Th1 or Th2 subset. Oligonucleotides 23-39 interleukin 4 Mus musculus 141-145 2974066-7 1988 In parallel experiments, the antisense IL-4 oligonucleotide blocked the proliferation of the Th2 clone and not the proliferation of the Th1 clone. Oligonucleotides 44-59 interleukin 4 Mus musculus 39-43