PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10807924-1	2000	An expression library for active site mutants of human topoisomerase IIalpha (TOP2alpha) was constructed by replacing the sequence encoding residues 793-808 with a randomized oligonucleotide cassette.	Oligonucleotides	175-190	DNA topoisomerase II alpha	Homo sapiens	78-87	
9207016-1	1997	We have analysed the DNA cleavage reaction of DNA gyrase using oligonucleotides annealed to a single-stranded M13 derivative containing a preferred gyrase cleavage site.	Oligonucleotides	63-79	DNA topoisomerase II alpha	Homo sapiens	46-56	
22841979-2	2012	To better understand how these enzymes act in both contexts, we determined the 2.9-A-resolution structure of the DNA cleavage core of human topoisomerase IIalpha (TOP2A) bound to a doubly nicked, 30-bp duplex oligonucleotide.	Oligonucleotides	209-224	DNA topoisomerase II alpha	Homo sapiens	163-168