PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35276003-0 2022 The Role of Long Non-coding RNA MALAT1 in Diabetic Polyneuropathy and the Impact of its Silencing in the Dorsal Root Ganglion by a DNA/RNA Heteroduplex Oligonucleotide. Oligonucleotides 152-167 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 32-38 29577871-4 2018 We performed lncRNA pulldown assay using biotinylated antisense oligonucleotides against MALAT1 and found MALAT1 interacted with Nrf2, suggesting Nrf2 is transcriptionally regulated by MALAT1. Oligonucleotides 64-80 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 89-95 29577871-4 2018 We performed lncRNA pulldown assay using biotinylated antisense oligonucleotides against MALAT1 and found MALAT1 interacted with Nrf2, suggesting Nrf2 is transcriptionally regulated by MALAT1. Oligonucleotides 64-80 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 106-112 29577871-4 2018 We performed lncRNA pulldown assay using biotinylated antisense oligonucleotides against MALAT1 and found MALAT1 interacted with Nrf2, suggesting Nrf2 is transcriptionally regulated by MALAT1. Oligonucleotides 64-80 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 106-112 27841943-9 2017 Using antisense oligonucleotides for MALAT1 and RNA immunoprecipitation assays, we demonstrate that MALAT1 recruits splice factor serine-arginine-rich splice factor 2 (SRSF2) to promote alternative splicing of PKCdeltaII. Oligonucleotides 16-32 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 100-106 35106589-2 2022 Herein, we report the synthesis and impact of stereopure phosphoryl guanidine-containing backbone linkages (PN linkages) to oligonucleotides acting through an RNase H-mediated mechanism, using Malat1 and C9orf72 as benchmarks. Oligonucleotides 124-140 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 193-199 35276003-3 2022 This study aimed to investigate the impact of MALAT1 silencing in dorsal root ganglion (DRG) sensory neurons, using a alpha-tocopherol-conjugated DNA/RNA heteroduplex oligonucleotide (Toc-HDO), on the peripheral nervous system of diabetic mice. Oligonucleotides 167-182 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 46-52 33625181-0 2021 Preclinical evaluation of [68Ga]Ga-MALAT-1-antisense oligonucleotides for specific PET imaging of MALAT-1 expressing tumours. Oligonucleotides 53-69 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 35-42 33625181-0 2021 Preclinical evaluation of [68Ga]Ga-MALAT-1-antisense oligonucleotides for specific PET imaging of MALAT-1 expressing tumours. Oligonucleotides 53-69 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 98-105 33625181-2 2021 METHODS: [68Ga]Ga labelling of MALAT-1 antisense oligonucleotides ([68Ga]Ga-MALAT-1-ASO) was synthesized by the conjugation of MALAT-1-NOTA-ASO and [68Ga] Ga3+. Oligonucleotides 49-65 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 31-38 33625181-2 2021 METHODS: [68Ga]Ga labelling of MALAT-1 antisense oligonucleotides ([68Ga]Ga-MALAT-1-ASO) was synthesized by the conjugation of MALAT-1-NOTA-ASO and [68Ga] Ga3+. Oligonucleotides 49-65 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 76-83 33625181-2 2021 METHODS: [68Ga]Ga labelling of MALAT-1 antisense oligonucleotides ([68Ga]Ga-MALAT-1-ASO) was synthesized by the conjugation of MALAT-1-NOTA-ASO and [68Ga] Ga3+. Oligonucleotides 49-65 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 76-83 32321759-7 2020 The Malat1 RNA is responsible for these effects, as antisense oligonucleotide-mediated inhibition of Malat1 also suppresses Maf and IL-10 levels. Oligonucleotides 62-77 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 4-10 33510962-4 2021 Methods: We generated a stereopure oligonucleotide (MALAT1-200) and assessed the potency, efficacy, and durability of its MALAT1 RNA-depleting activity compared with a stereorandom mixture, MALAT1-181, and other controls in in vitro assays, in vivo mouse and nonhuman primate (NHP) eyes, and ex vivo human retina cultures. Oligonucleotides 35-50 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 52-58 32321759-7 2020 The Malat1 RNA is responsible for these effects, as antisense oligonucleotide-mediated inhibition of Malat1 also suppresses Maf and IL-10 levels. Oligonucleotides 62-77 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 101-107 29487387-3 2018 Targeting MALAT1 by novel LNA-gapmeR antisense oligonucleotide antagonized MM cell proliferation and triggered apoptosis both in vitro and in vivo in a murine xenograft model of human MM. Oligonucleotides 47-62 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 10-16