PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30385727-0 2018 Antisense oligonucleotide-mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles. Oligonucleotides 10-25 ataxin 1 Mus musculus 35-43 32818920-0 2020 Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment. Oligonucleotides 10-25 ataxin 1 Mus musculus 66-74 32818920-4 2020 Here, we tested whether an antisense oligonucleotide (ASO)-mediated reduction of Atxn1 produced unwanted effects involving BACE1, CIC activity, or reduction in hippocampal neuronal precursor cells. Oligonucleotides 37-52 ataxin 1 Mus musculus 81-86 31394429-0 2019 Suppression of Mutant Protein Expression in SCA3 and SCA1 Mice Using a CAG Repeat-Targeting Antisense Oligonucleotide. Oligonucleotides 102-117 ataxin 1 Mus musculus 53-57 30385727-0 2018 Antisense oligonucleotide-mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles. Oligonucleotides 10-25 ataxin 1 Mus musculus 75-79 30385727-4 2018 Here, we investigated the therapeutic capability of an antisense oligonucleotide (ASO) targeting mouse Atxn1 in Atxn1154Q/2Q-knockin mice that manifest motor deficits and premature lethality. Oligonucleotides 65-80 ataxin 1 Mus musculus 103-108