PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35073217-2	2022	In this study, Malat1 antisense oligonucleotide (ASO) bearing GuNA was evaluated for target knockdown (KD) activity and tolerability.	Oligonucleotides	32-47	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	15-21	
33510962-0	2021	Stereochemistry Enhances Potency, Efficacy, and Durability of Malat1 Antisense Oligonucleotides In Vitro and In Vivo in Multiple Species.	Oligonucleotides	79-95	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	62-68	
33428963-9	2021	In experimental models, siRNA and antisense oligonucleotide (ASO) based strategy has been used for targeting MALAT1.	Oligonucleotides	44-59	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	109-115	
33510962-3	2021	We aimed to generate a stereopure MALAT1 (metastasis-associated lung adenocarcinoma transcript 1) antisense oligonucleotide as a tool to assess the impact stereochemistry has on potency, efficacy, and durability of oligonucleotide activity when delivered by intravitreal injection to eye.	Oligonucleotides	108-123	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	34-40	
33510962-6	2021	Findings in NHPs showed durable activity of the stereopure oligonucleotide in the retina, with nearly 95% reduction of MALAT1 RNA maintained for 4 months postinjection.	Oligonucleotides	59-74	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	119-125	
33510962-7	2021	Conclusions: An optimized, stereopure antisense oligonucleotide shows enhanced potency, efficacy, and durability of MALAT1 RNA depletion in the eye compared with its stereorandom counterpart in multiple preclinical models.	Oligonucleotides	48-63	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	116-122	
30591217-9	2019	NLRP3 expression was significantly suppressed by transfection with a MALAT1-targeting antisense oligonucleotide (ASO).	Oligonucleotides	96-111	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	69-75	
33473329-5	2021	The efficacies of the aptamers were tested by further conjugation with MALAT1-targeting antisense oligonucleotides (ASOs), and the expression levels of MALAT1 RNA were examined.	Oligonucleotides	98-114	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	71-77	
32865787-6	2020	This protocol describes the use of validated gapmer antisense oligonucleotides (ASOs) to knockdown human MALAT1, a nuclear-retained lncRNA that is upregulated in multiple cancer cells.	Oligonucleotides	62-78	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	105-111	
30294913-5	2019	Since the long non-coding RNA Metastasis Associated Lung Adenocarcinoma transcript 1 (MALAT1) was among the transcripts most highly increased in forced suspension culture, modified anti-sense oligonucleotides (ASO) were used to inhibit its expression.	Oligonucleotides	192-208	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	30-84	
30294913-5	2019	Since the long non-coding RNA Metastasis Associated Lung Adenocarcinoma transcript 1 (MALAT1) was among the transcripts most highly increased in forced suspension culture, modified anti-sense oligonucleotides (ASO) were used to inhibit its expression.	Oligonucleotides	192-208	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	86-92	
30548064-0	2019	Antisense Oligonucleotide-Conjugated Nanostructure-Targeting lncRNA MALAT1 Inhibits Cancer Metastasis.	Oligonucleotides	10-25	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	68-74	
30263873-12	2018	Depletion of MALAT1 in hADSC with antisense oligonucleotides resulted in exosomes without MALAT1.	Oligonucleotides	44-60	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	13-19	
26701265-3	2016	Here we report that genetic loss or systemic knockdown of Malat1 using antisense oligonucleotides (ASOs) in the MMTV (mouse mammary tumor virus)-PyMT mouse mammary carcinoma model results in slower tumor growth accompanied by significant differentiation into cystic tumors and a reduction in metastasis.	Oligonucleotides	81-97	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	58-64	
11824756-4	2001	In addition, two slightly different implementations of the MQ-TROSY-HCN experiment ensure optimal performance for small and larger oligonucleotides, respectively.	Oligonucleotides	131-147	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	68-71	
23243023-7	2013	Antisense oligonucleotides (ASO) blocking MALAT1 prevent metastasis formation after tumor implantation.	Oligonucleotides	10-26	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	42-48	
10826881-1	2000	Triple resonance HCN and HCNCH experiments are reliable methods of establishing sugar-to-base connectivity in the NMR spectra of isotopicaly labeled oligonucleotides.	Oligonucleotides	149-165	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	17-20