PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11449369-4	2001	Here we describe distinct CpG-containing oligonucleotide sequences which, in contrast to previously described CpG ODN, induced high amounts of IFN-alpha and IFN-beta in peripheral blood mononuclear cells (PBMC).	Oligonucleotides	41-56	interferon beta 1	Homo sapiens	157-165	
8662521-4	1996	Human monocytes transfected with pDNA or double-stranded oligonucleotides containing the ISS, but not those transfected with ISS-deficient pDNA or oligonucleotides, transcribed large amounts of interferon-alpha, interferon-beta, and interleukin-12.	Oligonucleotides	57-73	interferon beta 1	Homo sapiens	212-227	
6584908-4	1984	Using a synthetic oligonucleotide complementary to the human c-myc mRNA as the probe, we detected a more than 75% reduction in the c-myc hybridizable poly(A)+ RNA in the IFN-beta-treated cells.	Oligonucleotides	18-33	interferon beta 1	Homo sapiens	170-178	
1899864-10	1991	This IFN-gamma induced factor also binds to an oligonucleotide corresponding to -91 to -62 bp of the interferon-beta (IFN-beta) gene promoter, a region necessary for the induction of the IFN-beta gene by virus and double-stranded RNA.	Oligonucleotides	47-62	interferon beta 1	Homo sapiens	101-116	
1899864-10	1991	This IFN-gamma induced factor also binds to an oligonucleotide corresponding to -91 to -62 bp of the interferon-beta (IFN-beta) gene promoter, a region necessary for the induction of the IFN-beta gene by virus and double-stranded RNA.	Oligonucleotides	47-62	interferon beta 1	Homo sapiens	118-126	
1899864-10	1991	This IFN-gamma induced factor also binds to an oligonucleotide corresponding to -91 to -62 bp of the interferon-beta (IFN-beta) gene promoter, a region necessary for the induction of the IFN-beta gene by virus and double-stranded RNA.	Oligonucleotides	47-62	interferon beta 1	Homo sapiens	187-195	
2153928-6	1990	A synthetic double-stranded oligonucleotide corresponding to an authentic 30-base-pair (bp) region of the human IFN-beta promoter between positions -91 and -62 was found to confer virus inducibility upon the reporter CAT gene in HeLa cells.	Oligonucleotides	28-43	interferon beta 1	Homo sapiens	112-120	
2501084-8	1989	An oligonucleotide derived from the virus- and double-stranded RNA-inducible promoter of the interferon-beta 1 gene is able to bind IBP-1.	Oligonucleotides	3-18	interferon beta 1	Homo sapiens	93-110	
6159597-1	1980	From recently published data on the amino-terminal structures of human and mouse interferons, we have predicted and synthesised an oligonucleotide capable of priming specifically the reverse transcription of human fibroblast interferon mRNA present within a total mRNA population.	Oligonucleotides	131-146	interferon beta 1	Homo sapiens	214-235	
21877251-8	2011	Using oligonucleotide microarray, we demonstrated a dramatic increase in proinflammatory cytokine and chemokine transcripts (CXCL10, CXCL11, TNFSF10, CCL5, CCL4, CCL2, IFNB1, CCL20, IL-8, and CCL11).	Oligonucleotides	6-21	interferon beta 1	Homo sapiens	168-173	
21978158-6	2011	In particular, Lyn kinase oligonucleotides resulted in decreased expression of TLR-9-induced tumor necrosis factor alpha (TNF-alpha) but strongly upregulated canonical TLR-3-induced interferon beta (IFN-beta) and non-canonical TLR-3-induced NF-kappaB-dependent p35 (35kDa) subunit of interleukin 12 (IL-12p35) gene transcription.	Oligonucleotides	26-42	interferon beta 1	Homo sapiens	182-197	
21978158-6	2011	In particular, Lyn kinase oligonucleotides resulted in decreased expression of TLR-9-induced tumor necrosis factor alpha (TNF-alpha) but strongly upregulated canonical TLR-3-induced interferon beta (IFN-beta) and non-canonical TLR-3-induced NF-kappaB-dependent p35 (35kDa) subunit of interleukin 12 (IL-12p35) gene transcription.	Oligonucleotides	26-42	interferon beta 1	Homo sapiens	199-207	
19810673-2	2009	This study finds that the innate immune response (as measured by interferon-beta levels) to densely functionalized, oligonucleotide-modified nanoparticles is significantly less (up to a 25-fold decrease) when compared to a lipoplex carrying the same DNA sequence.	Oligonucleotides	116-131	interferon beta 1	Homo sapiens	65-80	
17273997-3	2007	TLR-3 and TLR-4 induce IFN-beta by activating IRF-3; TLR-9 induces IFN-alpha and IFN-beta through IRF-7, at least when engaged by type A CpG oligonucleotides (CpG-A) in plasmacytoid DC (pDC).	Oligonucleotides	141-157	interferon beta 1	Homo sapiens	81-89	
17273997-4	2007	In this issue of the European Journal of Immunology, it is demonstrated that TLR-9 induces IFN-beta when engaged by type B CpG oligonucleotides (CpG-B) in myeloid DC and macrophages.	Oligonucleotides	127-143	interferon beta 1	Homo sapiens	91-99