PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21505150-4 2011 In normal muscle homeostasis, Odc1 expression is regulated by age and sex, reflecting testosterone levels, as muscle of adult male mice expresses high levels of Odc1 compared with age-matched females and younger males. Testosterone 86-98 ornithine decarboxylase, structural 1 Mus musculus 30-34 24305501-7 2014 Among pathways that were differentially responsive to testosterone in prostate, we identified ornithine decarboxylase (Odc1), an enzyme in polyamine biosynthesis, as a testosterone-responsive gene that is unresponsive to rFst. Testosterone 54-66 ornithine decarboxylase, structural 1 Mus musculus 94-117 24305501-7 2014 Among pathways that were differentially responsive to testosterone in prostate, we identified ornithine decarboxylase (Odc1), an enzyme in polyamine biosynthesis, as a testosterone-responsive gene that is unresponsive to rFst. Testosterone 54-66 ornithine decarboxylase, structural 1 Mus musculus 119-123 24305501-7 2014 Among pathways that were differentially responsive to testosterone in prostate, we identified ornithine decarboxylase (Odc1), an enzyme in polyamine biosynthesis, as a testosterone-responsive gene that is unresponsive to rFst. Testosterone 168-180 ornithine decarboxylase, structural 1 Mus musculus 94-117 24305501-7 2014 Among pathways that were differentially responsive to testosterone in prostate, we identified ornithine decarboxylase (Odc1), an enzyme in polyamine biosynthesis, as a testosterone-responsive gene that is unresponsive to rFst. Testosterone 168-180 ornithine decarboxylase, structural 1 Mus musculus 119-123 11282290-2 2000 Daily injections of testosterone or dihydrotestosterone (DHT) into 60 day old female mice for 4 days increased renal ODC activity in a dose-dependent manner that reached up to 100-fold (testosterone) or 250-fold (DHT) above the baseline when the highest dose, 200 microg/mouse, was used. Testosterone 20-32 ornithine decarboxylase, structural 1 Mus musculus 117-120 19135973-3 2009 Sequential activation of these pathways leads to a drastic decrease of testosterone-induced ornithine decarboxylase, ODC, expression. Testosterone 71-83 ornithine decarboxylase, structural 1 Mus musculus 92-115 19135973-3 2009 Sequential activation of these pathways leads to a drastic decrease of testosterone-induced ornithine decarboxylase, ODC, expression. Testosterone 71-83 ornithine decarboxylase, structural 1 Mus musculus 117-120 17148758-2 2007 We report here that in CD1 mice there is marked sexual dimorphism affecting not only gland size and corticoid hormone secretion but also adrenal ornithine decarboxylase (ODC), polyamine, and catecholamine levels in which testosterone appears to be a major determinant. Testosterone 221-233 ornithine decarboxylase, structural 1 Mus musculus 145-168 15539552-0 2005 Testosterone down-regulates ornithine aminotransferase gene and up-regulates arginase II and ornithine decarboxylase genes for polyamines synthesis in the murine kidney. Testosterone 0-12 ornithine decarboxylase, structural 1 Mus musculus 93-116 15539552-2 2005 In the murine kidney, testosterone induced ODC gene expression and polyamine production, but it is unknown how OAT gene is expressed under androgen treatment. Testosterone 22-34 ornithine decarboxylase, structural 1 Mus musculus 43-46 15539552-6 2005 The results clearly indicate that pharmacological doses of testosterone simultaneously down-regulated the level of OAT protein and up-regulated the expression of arginase II and ODC genes. Testosterone 59-71 ornithine decarboxylase, structural 1 Mus musculus 178-181 15539552-10 2005 In conclusion, OAT and ODC genes are inversely regulated by testosterone in the mouse kidney. Testosterone 60-72 ornithine decarboxylase, structural 1 Mus musculus 23-26 15539552-11 2005 Consequently, in kidneys of testosterone-treated mice, L-arginine-derived ornithine produced by arginase II might be preferentially used by ODC for putrescine production rather than by OAT. Testosterone 28-40 ornithine decarboxylase, structural 1 Mus musculus 140-143 15276653-4 2004 Their interaction results in a decrease in testosterone-induced ODC activity and ODC mRNA level, and in differential modulation of SSAT expression. Testosterone 43-55 ornithine decarboxylase, structural 1 Mus musculus 64-67 15276653-4 2004 Their interaction results in a decrease in testosterone-induced ODC activity and ODC mRNA level, and in differential modulation of SSAT expression. Testosterone 43-55 ornithine decarboxylase, structural 1 Mus musculus 81-84 12709396-0 2003 Influence of testosterone on regulation of ODC, antizyme, and N1-SSAT gene expression in mouse kidney. Testosterone 13-25 ornithine decarboxylase, structural 1 Mus musculus 43-46 12709396-2 2003 In murine kidney, testosterone enhances gene expression of ornithine decarboxylase (ODC), the first enzyme in polyamine biosynthesis. Testosterone 18-30 ornithine decarboxylase, structural 1 Mus musculus 59-82 12709396-2 2003 In murine kidney, testosterone enhances gene expression of ornithine decarboxylase (ODC), the first enzyme in polyamine biosynthesis. Testosterone 18-30 ornithine decarboxylase, structural 1 Mus musculus 84-87 12709396-3 2003 In this study, we document the time course effect of testosterone on 1) gene expression of ODC, antizyme 1 (AZ1), and spermidine/spermine-N1-acetyltransferase (N1-SSAT); 2) ODC activity in proximal convoluted tubules (PCT) and cortical proximal straight tubules (CPST); and 3) renal polyamine levels. Testosterone 53-65 ornithine decarboxylase, structural 1 Mus musculus 91-94 12709396-3 2003 In this study, we document the time course effect of testosterone on 1) gene expression of ODC, antizyme 1 (AZ1), and spermidine/spermine-N1-acetyltransferase (N1-SSAT); 2) ODC activity in proximal convoluted tubules (PCT) and cortical proximal straight tubules (CPST); and 3) renal polyamine levels. Testosterone 53-65 ornithine decarboxylase, structural 1 Mus musculus 173-176 12709396-7 2003 In female kidneys, testosterone treatment sharply increased ODC mRNA and protein levels as well as ODC activity. Testosterone 19-31 ornithine decarboxylase, structural 1 Mus musculus 60-63 12709396-7 2003 In female kidneys, testosterone treatment sharply increased ODC mRNA and protein levels as well as ODC activity. Testosterone 19-31 ornithine decarboxylase, structural 1 Mus musculus 99-102 12709396-8 2003 Testosterone increased the expression of ODC in PCT and CPST over different time courses, which suggests that ODC activity is differentially regulated in distinct tubules. Testosterone 0-12 ornithine decarboxylase, structural 1 Mus musculus 41-44 12709396-8 2003 Testosterone increased the expression of ODC in PCT and CPST over different time courses, which suggests that ODC activity is differentially regulated in distinct tubules. Testosterone 0-12 ornithine decarboxylase, structural 1 Mus musculus 110-113 11139396-5 2001 Similarly, testosterone-induced ornithine decarboxylase (ODC) mRNA level and activity are decreased 2.8-7.7-fold when the androgen is applied together with CB 3717. Testosterone 11-23 ornithine decarboxylase, structural 1 Mus musculus 32-55 11139396-5 2001 Similarly, testosterone-induced ornithine decarboxylase (ODC) mRNA level and activity are decreased 2.8-7.7-fold when the androgen is applied together with CB 3717. Testosterone 11-23 ornithine decarboxylase, structural 1 Mus musculus 57-60 11139396-7 2001 Our results document a substantial negative regulation of c-Met and ODC gene expression as a result of the cross-talk between testosterone-activated and HGF-activated pathways and suggest a sex-differentiated response to injury of mouse kidneys. Testosterone 126-138 ornithine decarboxylase, structural 1 Mus musculus 68-71 11282290-2 2000 Daily injections of testosterone or dihydrotestosterone (DHT) into 60 day old female mice for 4 days increased renal ODC activity in a dose-dependent manner that reached up to 100-fold (testosterone) or 250-fold (DHT) above the baseline when the highest dose, 200 microg/mouse, was used. Testosterone 43-55 ornithine decarboxylase, structural 1 Mus musculus 117-120 11282290-3 2000 Administration of flutamide concurrently with testosterone (75 microg/mouse) caused a potent decrease of ODC induction in a dose-dependent manner, suppressing the enzyme activity at the doses of 0.1 and 0.5 mg/mouse by about 88 and 95%, respectively. Testosterone 46-58 ornithine decarboxylase, structural 1 Mus musculus 105-108 11282290-4 2000 In contrast, estradiol at the doses of 0.5 and 1 mg/mouse induced a significant stimulation of renal ODC activity in a dose-dependent manner when it was given alone or in combination with testosterone. Testosterone 188-200 ornithine decarboxylase, structural 1 Mus musculus 101-104 10232597-15 1999 Similar results were obtained with C57BL/6 mice, where testosterone treatment at similar dosage resulted in a 2-fold increase in ODC activity in the ventral prostate and prior oral feeding with 0.2% GTPs resulted in 40% inhibition in this induction. Testosterone 55-67 ornithine decarboxylase, structural 1 Mus musculus 129-132 11007319-8 2000 Testosterone increased ODC activity in the proximal tubule substantially and to a minor extent in other nephron segments. Testosterone 0-12 ornithine decarboxylase, structural 1 Mus musculus 23-26 11007319-9 2000 In situ hybridization showed ODC messenger ribonucleic acid (mRNA) to be absent in kidneys of untreated females but abundant in the cortex and the outer stripe of the outer medulla of testosterone-treated female mice. Testosterone 184-196 ornithine decarboxylase, structural 1 Mus musculus 29-32 11007319-12 2000 The testosterone-inducible ODC is localized mainly in the proximal tubule, but is also present in distal tubules and collecting ducts. Testosterone 4-16 ornithine decarboxylase, structural 1 Mus musculus 27-30 9062893-6 1997 Developing tumours, especially ascitic, altered the renal activity of OAT and ODC, but not of arginase, in testosterone-untreated mice. Testosterone 107-119 ornithine decarboxylase, structural 1 Mus musculus 78-81 9194572-1 1997 Catecholamine depletion, evoked by reserpine, dramatically impaired (5-fold) the testosterone-induced increase of ornithine decarboxylase (ODC) activity in female mouse kidney. Testosterone 81-93 ornithine decarboxylase, structural 1 Mus musculus 114-137 9194572-1 1997 Catecholamine depletion, evoked by reserpine, dramatically impaired (5-fold) the testosterone-induced increase of ornithine decarboxylase (ODC) activity in female mouse kidney. Testosterone 81-93 ornithine decarboxylase, structural 1 Mus musculus 139-142 9194572-5 1997 Northern blot analysis revealed that the ODC mRNA level, that was increased 10-fold by testosterone, was decreased 2-fold in catecholamine-depleted hypertrophic kidney. Testosterone 87-99 ornithine decarboxylase, structural 1 Mus musculus 41-44 9194572-6 1997 Thus, ODC transcript level, lowered by reserpine, correlated partially with an attenuated response of ODC activity to testosterone. Testosterone 118-130 ornithine decarboxylase, structural 1 Mus musculus 6-9 9194572-6 1997 Thus, ODC transcript level, lowered by reserpine, correlated partially with an attenuated response of ODC activity to testosterone. Testosterone 118-130 ornithine decarboxylase, structural 1 Mus musculus 102-105 9194572-8 1997 It is concluded that catecholamines could be involved together with testosterone in regulation of the ODC gene expression in mouse kidney. Testosterone 68-80 ornithine decarboxylase, structural 1 Mus musculus 102-105 8574884-7 1995 Following testosterone treatment, ODC mRNA in the pars convoluta was expressed with a stronger intensity than that in the vehicle-injected animals. Testosterone 10-22 ornithine decarboxylase, structural 1 Mus musculus 34-37 7557274-2 1995 Neuronal, but not circulating catecholamines, regulate the induction of ornithine decarboxylase (ODC) by testosterone in the mouse kidney. Testosterone 105-117 ornithine decarboxylase, structural 1 Mus musculus 72-95 7557274-2 1995 Neuronal, but not circulating catecholamines, regulate the induction of ornithine decarboxylase (ODC) by testosterone in the mouse kidney. Testosterone 105-117 ornithine decarboxylase, structural 1 Mus musculus 97-100 7557274-6 1995 Benserazide and haloperidol decreased the induction of renal ODC produced by testosterone in female mice. Testosterone 77-89 ornithine decarboxylase, structural 1 Mus musculus 61-64 7557274-8 1995 Renal denervation produced a partial inhibition of renal ODC in male mice and decreased the induction of ODC elicited by testosterone in female mice. Testosterone 121-133 ornithine decarboxylase, structural 1 Mus musculus 105-108 7474658-3 1995 Only in the case of renal hypertrophy produced by testosterone administration was there a significant increase in ODC activity and putrescine content in the kidneys. Testosterone 50-62 ornithine decarboxylase, structural 1 Mus musculus 114-117 8307774-0 1993 Heterogeneous expression of ornithine decarboxylase gene in the proximal tubule of the mouse kidney following testosterone treatment. Testosterone 110-122 ornithine decarboxylase, structural 1 Mus musculus 28-51 7780833-1 1995 Administration of testosterone to female mice causes hypertrophy of their kidneys with spectacular induction of ornithine decarboxylase and significant increase in the level of putrescine. Testosterone 18-30 ornithine decarboxylase, structural 1 Mus musculus 112-135 7780833-12 1995 The study showed testosterone-induced differential changes in the activity of two enzymes involved in ornithine biosynthesis and catabolism which accompanied ODC induction in female mouse kidney. Testosterone 17-29 ornithine decarboxylase, structural 1 Mus musculus 158-161 8307774-1 1993 The expression of the ornithine decarboxylase (ODC) gene in the mouse kidney following testosterone treatment was examined using in situ hybridization histochemistry. Testosterone 87-99 ornithine decarboxylase, structural 1 Mus musculus 22-45 8307774-1 1993 The expression of the ornithine decarboxylase (ODC) gene in the mouse kidney following testosterone treatment was examined using in situ hybridization histochemistry. Testosterone 87-99 ornithine decarboxylase, structural 1 Mus musculus 47-50 8307774-7 1993 A marked increase in ODC mRNA was exclusively detected in the proximal tubule of the renal cortex in the testosterone-treated animals. Testosterone 105-117 ornithine decarboxylase, structural 1 Mus musculus 21-24 8307774-10 1993 These results indicate that testosterone induces the expression of the ODC gene in the proximal tubule of the renal cortex, leading to the increase in ODC activity in the same region. Testosterone 28-40 ornithine decarboxylase, structural 1 Mus musculus 71-74 8307774-10 1993 These results indicate that testosterone induces the expression of the ODC gene in the proximal tubule of the renal cortex, leading to the increase in ODC activity in the same region. Testosterone 28-40 ornithine decarboxylase, structural 1 Mus musculus 151-154 8318020-2 1993 We used three different stimuli which are well known to enhance ornithine decarboxylase activity in their appropriate target tissues: (i) testosterone in female kidney, (ii) a phorbol ester in epidermis and (iii) partial hepatectomy in liver. Testosterone 138-150 ornithine decarboxylase, structural 1 Mus musculus 64-87 8357843-2 1993 In the testosterone-induced hypertrophic and antifolate (N10-propargyl,5,6-dideazafolic acid, CB 3717)-induced hyperplastic mouse kidney models, a marked increase of two diamine levels--putrescine and cadaverine--occurred which paralleled induced ornithine decarboxylase (ODC) activity. Testosterone 7-19 ornithine decarboxylase, structural 1 Mus musculus 247-270 8357843-2 1993 In the testosterone-induced hypertrophic and antifolate (N10-propargyl,5,6-dideazafolic acid, CB 3717)-induced hyperplastic mouse kidney models, a marked increase of two diamine levels--putrescine and cadaverine--occurred which paralleled induced ornithine decarboxylase (ODC) activity. Testosterone 7-19 ornithine decarboxylase, structural 1 Mus musculus 272-275 8318020-5 1993 The human transgene-derived ornithine decarboxylase activity in kidney was unaffected by testosterone treatment, but responded in skin to application of the phorbol ester and likewise was clearly enhanced in regenerating liver. Testosterone 89-101 ornithine decarboxylase, structural 1 Mus musculus 28-51 8318020-6 1993 Although mouse endogenous ornithine decarboxylase mRNA levels were distinctly elevated after testosterone, this treatment did not influence the accumulation of the human transgene-derived mRNA. Testosterone 93-105 ornithine decarboxylase, structural 1 Mus musculus 26-49 8429279-0 1993 Induction of ornithine decarboxylase immunoreactivity in the male mouse kidney following testosterone treatment: an axial heterogeneity in the proximal tubule. Testosterone 89-101 ornithine decarboxylase, structural 1 Mus musculus 13-36 8429279-1 1993 The effect of testosterone on the activity of ornithine decarboxylase (ODC), its protein level and immunocytochemical distribution were examined in the mouse kidney. Testosterone 14-26 ornithine decarboxylase, structural 1 Mus musculus 46-69 8429279-1 1993 The effect of testosterone on the activity of ornithine decarboxylase (ODC), its protein level and immunocytochemical distribution were examined in the mouse kidney. Testosterone 14-26 ornithine decarboxylase, structural 1 Mus musculus 71-74 8429279-4 1993 Renal ODC activity and the content of the enzyme were markedly increased after testosterone treatment. Testosterone 79-91 ornithine decarboxylase, structural 1 Mus musculus 6-9 8429279-5 1993 Histologically, few cells that were obviously immunoreactive to ODC were observed in the control animals and in the testosterone-treated animals a marked increase in ODC immunoreactivity was observed only in the cortex. Testosterone 116-128 ornithine decarboxylase, structural 1 Mus musculus 64-67 8429279-5 1993 Histologically, few cells that were obviously immunoreactive to ODC were observed in the control animals and in the testosterone-treated animals a marked increase in ODC immunoreactivity was observed only in the cortex. Testosterone 116-128 ornithine decarboxylase, structural 1 Mus musculus 166-169 8429279-9 1993 These results show that testosterone treatment induces an increase in ODC content in certain cells located in the proximal tubule of the cortex. Testosterone 24-36 ornithine decarboxylase, structural 1 Mus musculus 70-73 2497140-2 1989 The amount of ODC protein was determined in crude extracts from the kidney of testosterone-treated mice, regenerating rat liver and human thyroid carcinoma, with purified mouse kidney or rat liver enzyme as standard. Testosterone 78-90 ornithine decarboxylase, structural 1 Mus musculus 14-17 2083533-2 1990 Testosterone (1 mg per mouse) induced a marked increase in ornithine decarboxylase activity of the mouse kidney, whereas no significant immunohistochemical difference was observed either in immunoreactivity or its localization. Testosterone 0-12 ornithine decarboxylase, structural 1 Mus musculus 59-82 1417915-0 1992 Catecholamines are required for testosterone induction of ornithine decarboxylase in the mouse kidney. Testosterone 32-44 ornithine decarboxylase, structural 1 Mus musculus 58-81 2340113-1 1990 Based on methods for ornithine-decarboxylase purification published previously we developed an improved procedure for purification of the enzyme from the kidneys of testosterone-treated NMRI mice. Testosterone 165-177 ornithine decarboxylase, structural 1 Mus musculus 21-44 3896241-3 1985 The elution patterns of ornithine decarboxylase activity and immunoreactive enzyme protein in the kidneys of untreated and testosterone-treated male mice did not differ otherwise than in order of magnitude. Testosterone 123-135 ornithine decarboxylase, structural 1 Mus musculus 24-47 3386633-9 1988 For GUS, ODC, and RP-2 mRNAs, but not KAP mRNA, induction of synthesis was rapidly reversed after testosterone removal. Testosterone 98-110 ornithine decarboxylase, structural 1 Mus musculus 9-12 3092827-0 1986 Ornithine decarboxylase activity and actin polymerization in testosterone--stimulated mouse kidney. Testosterone 61-73 ornithine decarboxylase, structural 1 Mus musculus 0-23 3178765-5 1988 Administration of testosterone to female mice, a procedure known to prolong the half-life of renal ODC, increased both ODC activity and the content of ODC-antizyme complex, but decreased the antizyme/ODC ratio in the kidney. Testosterone 18-30 ornithine decarboxylase, structural 1 Mus musculus 99-102 3178765-5 1988 Administration of testosterone to female mice, a procedure known to prolong the half-life of renal ODC, increased both ODC activity and the content of ODC-antizyme complex, but decreased the antizyme/ODC ratio in the kidney. Testosterone 18-30 ornithine decarboxylase, structural 1 Mus musculus 119-122 3178765-5 1988 Administration of testosterone to female mice, a procedure known to prolong the half-life of renal ODC, increased both ODC activity and the content of ODC-antizyme complex, but decreased the antizyme/ODC ratio in the kidney. Testosterone 18-30 ornithine decarboxylase, structural 1 Mus musculus 119-122 3757919-1 1986 The activity of ornithine decarboxylase in androgen-dependent mouse mammary tumor (Shionogi Carcinoma 115) was reduced to 25% by castration of tumor-bearing mice and restored to the normal level 12 h after administration of testosterone or 5 alpha-dihydrotestosterone. Testosterone 224-236 ornithine decarboxylase, structural 1 Mus musculus 16-39 6519353-1 1984 Renal ornithine decarboxylase (ODC) activity was evaluated in normal female, male, testosterone-treated female and androgen-insensitive Tfm/Y mice for its heat sensitivity and in vivo half-life. Testosterone 83-95 ornithine decarboxylase, structural 1 Mus musculus 6-29 3964747-11 1985 However, flutamide (up to 650 micrograms/day) given concomitantly with testosterone (40 micrograms/day) almost completely abolished the testosterone-induced increase in ODC. Testosterone 71-83 ornithine decarboxylase, structural 1 Mus musculus 169-172 3964747-11 1985 However, flutamide (up to 650 micrograms/day) given concomitantly with testosterone (40 micrograms/day) almost completely abolished the testosterone-induced increase in ODC. Testosterone 136-148 ornithine decarboxylase, structural 1 Mus musculus 169-172 6519353-1 1984 Renal ornithine decarboxylase (ODC) activity was evaluated in normal female, male, testosterone-treated female and androgen-insensitive Tfm/Y mice for its heat sensitivity and in vivo half-life. Testosterone 83-95 ornithine decarboxylase, structural 1 Mus musculus 31-34 4724183-7 1973 In the kidney, following testosterone administration, ornithine decarboxylase activity was found to be substantially elevated, whereas that of histidine decarboxylase was depressed. Testosterone 25-37 ornithine decarboxylase, structural 1 Mus musculus 54-77 6477895-6 1984 The fraction of total protein synthesis represented by renal ornithine decarboxylase was increased at least 25-fold by testosterone treatment of female mice and was found to be about 1.1% in the fully induced androgen-treated female. Testosterone 119-131 ornithine decarboxylase, structural 1 Mus musculus 61-84 6477638-0 1984 The effect of testosterone on the half-life of ornithine decarboxylase-mRNA in mouse kidney. Testosterone 14-26 ornithine decarboxylase, structural 1 Mus musculus 47-70 6477638-1 1984 The effect of testosterone on half-lives of ornithine decarboxylase and its mRNA in mouse kidney was studied. Testosterone 14-26 ornithine decarboxylase, structural 1 Mus musculus 44-67 6598355-11 1984 In this regard it is of interest to note that chronic treatment of mice with pharmacological doses of testosterone prolongs the half-life of ODC protein four- to tenfold. Testosterone 102-114 ornithine decarboxylase, structural 1 Mus musculus 141-144 6413866-8 1983 We now report that testosterone evokes a rapid (less than 30 s), transient increase in ODC activity and a sustained increase in polyamines in kidney cortex. Testosterone 19-31 ornithine decarboxylase, structural 1 Mus musculus 87-90 6853503-9 1983 After administration of a single dose of testosterone (10 mg) to female mice, an increased immunoreactive ornithine decarboxylase concentration was detected as soon as 2 h, and rose sharply between 8 and 24 h after steroid administration. Testosterone 41-53 ornithine decarboxylase, structural 1 Mus musculus 106-129 6880806-6 1983 The elevation of ornithine decarboxylase activity in the gastrocnemius by testosterone was reflected in an increased content of the polyamines in the muscle. Testosterone 74-86 ornithine decarboxylase, structural 1 Mus musculus 17-40 6401734-4 1983 It was found that treatment of female mice with testosterone produced a 400-fold increase in ornithine decarboxylase protein in the kidney within 4-5 days. Testosterone 48-60 ornithine decarboxylase, structural 1 Mus musculus 93-116 7164704-2 1982 L-Ornithine decarboxylase was purified to apparent homogeneity from the kidneys of testosterone-treated mice. Testosterone 83-95 ornithine decarboxylase, structural 1 Mus musculus 2-25 6175515-0 1982 Effects of testosterone on renal ornithine decarboxylase and kidney function. Testosterone 11-23 ornithine decarboxylase, structural 1 Mus musculus 33-56 6175515-1 1982 Testosterone injection caused a 2,000% increase in renal ornithine decarboxylase activity in intact male mice. Testosterone 0-12 ornithine decarboxylase, structural 1 Mus musculus 57-80 6797167-0 1981 Decarboxylation of ornithine and lysine by ornithine decarboxylase from kidneys of testosterone treated mice. Testosterone 83-95 ornithine decarboxylase, structural 1 Mus musculus 43-66 6457504-1 1980 Testosterone administration to gonadectomized male mice, besides giving rise to a distinct hypertrophy of the kidneys, results in a large increase in renal ornithine decarboxylase activity and accumulation of polyamines. Testosterone 0-12 ornithine decarboxylase, structural 1 Mus musculus 156-179 6457504-4 1980 Although the injection of mercuric chloride to testosterone treated mice decreased the stimulation of ornithine decarboxylase activity it did not prevent the increase in the concentration of putrescine. Testosterone 47-59 ornithine decarboxylase, structural 1 Mus musculus 102-125 6366788-7 1984 After a single dose of testosterone, renal OrnDCase mRNA concentration increased as soon as 6 hr and peaked 24 hr after steroid injection, as measured by RNA blot hybridization. Testosterone 23-35 ornithine decarboxylase, structural 1 Mus musculus 43-51 6582509-6 1984 A similar size mRNA was found in mouse kidney and was more abundant in the kidneys of mice treated with testosterone, an inducer of OrnDCase activity in that tissue. Testosterone 104-116 ornithine decarboxylase, structural 1 Mus musculus 132-140 6580640-5 1983 The ornithine decarboxylase inhibitor alpha-difluoromethylornithine (5 mM) suppressed the testosterone-induced increase in polyamine levels and rates of endocytosis, hexose transport, and amino acid transport, measured by horseradish peroxidase, [14C]aminoisobutyric acid, and deoxy[3H]glucose uptake. Testosterone 90-102 ornithine decarboxylase, structural 1 Mus musculus 4-27 6371845-2 1983 Although androgens increase many renal proteins, beta-glucuronidase and ODC are distinguished by exquisite genetic regulation of the magnitude of the response induced by testosterone. Testosterone 170-182 ornithine decarboxylase, structural 1 Mus musculus 72-75 506764-2 1979 Injections of 1,3-diaminopropane resulted in an almost total suppression of the testosterone induced stimulation of ornithine decarboxylase activity and prevented the accumulation of putrescine and spermidine in the kidneys. Testosterone 80-92 ornithine decarboxylase, structural 1 Mus musculus 116-139 654930-3 1978 The activity or ornithine decarboxylase was enhanced to values of more than 1 000 times the control level within a few days of testosterone substitution. Testosterone 127-139 ornithine decarboxylase, structural 1 Mus musculus 16-39 30566531-0 2018 New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motility. Testosterone 147-159 ornithine decarboxylase, structural 1 Mus musculus 73-96