PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25656365-6	2015	In adult rats, the overall renal AQP1 protein and mRNA expression was ~80% and ~40% higher, respectively, in males than in females, downregulated by gonadectomy in both sexes and upregulated strongly by testosterone and moderately by progesterone treatment; estradiol treatment had no effect.	Testosterone	203-215	aquaporin 1	Rattus norvegicus	33-37	
30430402-9	2019	Expression of AQP-1, AQP-2 and AQP-9 were detected in vas deferens but not AQP-5 and AQP-7, and the levels of these proteins were increased by testosterone treatment mainly at the apical membrane of vas deferens epithelium.	Testosterone	143-155	aquaporin 1	Rattus norvegicus	14-19	
30430402-10	2019	In conclusion, increased in vas deferens fluid secretion rate under testosterone influence mediated via the up-regulation of AQP-1, 2 and 9 might be important for vas deferens fluid homeostasis in order to ensure normal male fertility.	Testosterone	68-80	aquaporin 1	Rattus norvegicus	125-139	
28024836-6	2017	RESULTS: Testosterone caused MAP, AQP-1, 2, 4, 6 and 7 protein and mRNA levels in kidneys to increase while AQP-3 protein and mRNA levels in kidneys to decrease (p < 0.05).	Testosterone	9-21	aquaporin 1	Rattus norvegicus	34-54	
28024836-9	2017	CONCLUSIONS: Elevated expression of AQP-1, 2, 4, 6 and 7 under testosterone influence in kidneys could lead to increase H2O reabsorption which eventually lead to increase in blood pressure.	Testosterone	63-75	aquaporin 1	Rattus norvegicus	36-41	
26198330-2	2015	This study aimed to investigate effect of testosterone on uterine AQP-1, 5, and 7 expressions in order to explain the reported reduction in uterine fluid volume under testosterone influence.	Testosterone	42-54	aquaporin 1	Rattus norvegicus	66-71	
26198330-2	2015	This study aimed to investigate effect of testosterone on uterine AQP-1, 5, and 7 expressions in order to explain the reported reduction in uterine fluid volume under testosterone influence.	Testosterone	167-179	aquaporin 1	Rattus norvegicus	66-71	
26198330-7	2015	Levels of AQP-1 mRNA were elevated in rats receiving either estrogen or testosterone-only treatment; however, levels of AQP-5 and 7 mRNAs were elevated in rats receiving testosterone-only treatment.	Testosterone	72-84	aquaporin 1	Rattus norvegicus	10-15	
26198330-8	2015	In rats pre-treated with estrogen, testosterone treatment resulted in higher AQP-1, 5, and 7 mRNA levels compared to vehicle treatment.	Testosterone	35-47	aquaporin 1	Rattus norvegicus	77-82	
26198330-10	2015	Immunofluorescence study showed that AQP-1 was highly distributed in uterine lumenal epithelium following estrogen or testosterone-only treatment.	Testosterone	118-130	aquaporin 1	Rattus norvegicus	37-42	
26198330-12	2015	Testosterone-induced up-regulation of AQP-1, 5, and 7 expressions in uterus could explain the observed reduction in uterine fluid volume as reported under this condition.	Testosterone	0-12	aquaporin 1	Rattus norvegicus	38-43