PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25961225-8 2010 Other DHEA and testosterone-derived metabolites, namely epiandrosterone and 5alpha-androstane-3beta,17beta-diol, are also substrates for the CYP7B1 and their 7alpha-hydroxylated products were also converted into the 7beta epimer by the 11beta-HSD1. Testosterone 15-27 hydroxysteroid 11-beta dehydrogenase 1 Homo sapiens 236-247 20410225-0 2010 Testosterone stimulates adipose tissue 11beta-hydroxysteroid dehydrogenase type 1 expression in a depot-specific manner in children. Testosterone 0-12 hydroxysteroid 11-beta dehydrogenase 1 Homo sapiens 39-81 20410225-3 2010 OBJECTIVE: Our objective was to study 11beta-HSD1 mRNA expression in abdominal sc and omental (om) adipose tissue in children after in vitro testosterone and cortisol treatment. Testosterone 141-153 hydroxysteroid 11-beta dehydrogenase 1 Homo sapiens 38-49 20410225-6 2010 RESULTS: Testosterone treatment up-regulated 11beta-HSD1 mRNA expression compared with control incubations in the absence of testosterone (P < 0.05) in om adipose tissue. Testosterone 9-21 hydroxysteroid 11-beta dehydrogenase 1 Homo sapiens 45-56 20410225-7 2010 Testosterone and cortisol both increased 11beta-HSD1 mRNA expression in om but not sc adipose tissue in a depot-specific manner by 2.5- and 2.9-fold, respectively (P < 0.001). Testosterone 0-12 hydroxysteroid 11-beta dehydrogenase 1 Homo sapiens 41-52 20410225-11 2010 CONCLUSIONS: Testosterone and cortisol stimulated 11beta-HSD1 and H6PDH mRNA expression and 11beta-HSD1 activity in om but not in sc adipose tissue. Testosterone 13-25 hydroxysteroid 11-beta dehydrogenase 1 Homo sapiens 50-61 20410225-11 2010 CONCLUSIONS: Testosterone and cortisol stimulated 11beta-HSD1 and H6PDH mRNA expression and 11beta-HSD1 activity in om but not in sc adipose tissue. Testosterone 13-25 hydroxysteroid 11-beta dehydrogenase 1 Homo sapiens 92-103