PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22918704-0 2013 Osteoprotegerin levels decrease during testosterone therapy in aging men and are associated with changed distribution of regional fat. Testosterone 39-51 TNF receptor superfamily member 11b Homo sapiens 0-15 23211475-0 2013 Plasma osteoprotegerin is associated with testosterone levels but unaffected by pioglitazone treatment in patients with polycystic ovary syndrome. Testosterone 42-54 TNF receptor superfamily member 11b Homo sapiens 7-22 23211475-8 2013 In PCOS patients (no.=30), OPG levels were positively associated with testosterone (r=0.43), PRL (r=0.47), Pyridinoline cross-linked carboxyterminal telopeptide of type I collagen (r=0.43), and hip BMD, whereas inverse associations were found between OPG levels and triglyceride (r=-0.49) and free fatty acid levels during euglycemic clamps (r=-0.38), all p<0.05. Testosterone 70-82 TNF receptor superfamily member 11b Homo sapiens 27-30 22918704-3 2013 We investigated the effect of testosterone therapy on OPG levels in aging men with low normal bioavailable testosterone levels. Testosterone 30-42 TNF receptor superfamily member 11b Homo sapiens 54-57 22918704-11 2013 OPG levels decreased during testosterone therapy (from 2.0 (1.9-2.5) to 1.9 (1.6-2.2) ng/ml, p<0.05 vs. placebo), whereas CRP levels were unchanged (n=38). Testosterone 28-40 TNF receptor superfamily member 11b Homo sapiens 0-3 22918704-13 2013 OPG levels decreased during testosterone therapy suggesting decreased cardiovascular risk. Testosterone 28-40 TNF receptor superfamily member 11b Homo sapiens 0-3 20974706-6 2011 RESULTS: OPG was significantly lower in PCOS and related negatively to free testosterone and positively to estradiol (E(2)) levels. Testosterone 76-88 TNF receptor superfamily member 11b Homo sapiens 9-12 21903971-7 2012 In patients without androgen deprivation therapy, serum OPG levels were correlated with the levels of total testosterone (r = 0.508, P = .001) and bioavailable testosterone (r = 0.311, P = .037). Testosterone 110-122 TNF receptor superfamily member 11b Homo sapiens 57-60 21903971-7 2012 In patients without androgen deprivation therapy, serum OPG levels were correlated with the levels of total testosterone (r = 0.508, P = .001) and bioavailable testosterone (r = 0.311, P = .037). Testosterone 163-175 TNF receptor superfamily member 11b Homo sapiens 57-60 22100799-1 2011 BACKGROUND: It has been suggested that increased testosterone secretion in postmenopausal obese women might have some protective effect on bone tissue; the association might be significantly influenced by the RANKL/RANK/OPG system. Testosterone 49-61 TNF receptor superfamily member 11b Homo sapiens 220-223 18252198-4 2008 In MCF-7 cells, which predominantly express ER-alpha, 17beta-estradiol and testosterone dose-dependently decreased OPG mRNA levels and protein secretion by 70 and 65%, respectively (p<0.0001 by ANOVA). Testosterone 75-87 TNF receptor superfamily member 11b Homo sapiens 115-118 18252198-5 2008 The inhibition of OPG production by 17beta-estradiol and testosterone was specifically prevented by the pure anti-estrogen ICI 182,780, and the testosterone effect was prevented by an aromatase inhibitor. Testosterone 57-69 TNF receptor superfamily member 11b Homo sapiens 18-21 32338102-4 2020 Correlation analysis showed a positive correlation between OPG and total testosterone levels in the PCOS group (r = 0.277, p = .045). Testosterone 73-85 TNF receptor superfamily member 11b Homo sapiens 59-62 12153751-8 2002 Moreover, 5alpha-DHT and testosterone also decreased OPG protein secretion by 40-46% in the untransformed MSC cells, while OHF stimulated it. Testosterone 25-37 TNF receptor superfamily member 11b Homo sapiens 53-56 12086350-6 2002 OPG levels correlated inversely with serum bioavailable testosterone levels in men = 50 years (R = -0.27, p < 0.001), but no associations were present with either estrogen or testosterone levels in the women. Testosterone 56-68 TNF receptor superfamily member 11b Homo sapiens 0-3 26311162-3 2015 RESULTS: OPG correlated significantly with age (Spearman"s rho (r) = 0.359, p < 0.001), cystatin C (r = 0.298, p < 0.001), E2 (r = 0.160, p = 0.028) and free testosterone index (FTI) (r = -0.230, p = 0.001). Testosterone 164-176 TNF receptor superfamily member 11b Homo sapiens 9-12