PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34363387-4	2021	We hypothesized that Sirt1 and/or Nrf2 might be involved in regulating the oxidant/antioxidant environment of Leydig cells, and therefore testosterone production.	Testosterone	138-150	NFE2 like bZIP transcription factor 2	Rattus norvegicus	34-38	
34363387-8	2021	Activation of rat Leydig cells Sirt1 with honokiol or of Nrf2 with sulforaphane resulted in the maintenance of testosterone production despite the exposure of the cells to oxidizing agent.	Testosterone	111-123	NFE2 like bZIP transcription factor 2	Rattus norvegicus	57-61	
31475489-0	2019	[Electroacupuncture intervention increases testosterone level of aged rats by activating ERK/Nrf2/HO-1 signaling of Leydig cells].	Testosterone	43-55	NFE2 like bZIP transcription factor 2	Rattus norvegicus	93-97	
31475489-11	2019	CONCLUSION: EA intervention may increase testosterone level of the aged rats, which may be related to its effects in triggering ERK /Nrf2 /HO-1 signaling (anti-oxidative stress signal pathway) in the testis.	Testosterone	41-53	NFE2 like bZIP transcription factor 2	Rattus norvegicus	133-137	
23756138-6	2013	However, whether Nrf2-ARE pathway is activated after testosterone administration has not been studied in aged rats.	Testosterone	53-65	NFE2 like bZIP transcription factor 2	Rattus norvegicus	17-21	
34337184-7	2021	Adipose and body weights, plasma leptin and adiponectin, adipose and hypothalamic leptin and triglyceride, adipose uric acid, hypothalamic Nrf2, catalase and nitric oxide were reduced following gestational testosterone exposure.	Testosterone	206-218	NFE2 like bZIP transcription factor 2	Rattus norvegicus	139-143	
34277360-8	2021	Exposure to gestational testosterone caused reduction in fetal and placental weights, placental Nrf2 and adiponectin.	Testosterone	24-36	NFE2 like bZIP transcription factor 2	Rattus norvegicus	96-100	
33519479-0	2020	Piceatannol Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by Modulation of Nrf2/HO-1/NFkappaB Axis.	Testosterone	23-35	NFE2 like bZIP transcription factor 2	Rattus norvegicus	98-102	
33519479-16	2020	Immunohistochemically, PIC SNEDDS protected against the testosterone-induced increased expression of tumor necrosis factor alpha (TNF-alpha), interleukin-6 (IL-6), cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), nuclear factor kappa B (NFkappaB) and also offered protection against the decline in Nrf2 expression.	Testosterone	56-68	NFE2 like bZIP transcription factor 2	Rattus norvegicus	315-319