PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12107646-10 2002 6-Nitrochrysene induced CYP1 mRNAs to the same extent or more potently than chrysene. 6-nitrochrysene 0-15 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 24-28 11033235-0 2000 Induction of cytochrome P450 1A1 in human hepatoma HepG2 cells by 6-nitrochrysene. 6-nitrochrysene 66-81 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 13-32 11033235-5 2000 Treatment of human lung carcinoma NCI-H322 cells with 6-NC increased benzo[a]pyrene hydroxylase activity and CYP1A1 protein and mRNA levels. 6-nitrochrysene 54-58 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 109-115 11033235-6 2000 These results demonstrate that 6-NC is an inducer of human CYP1A1 and the induction occurs at a transcriptional level in HepG2 cells. 6-nitrochrysene 31-35 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 59-65 11033235-7 2000 The ability of 6-NC to induce liver and lung CYP1A1 may be an important factor to consider in assessing 6-NC metabolism and toxicity in humans. 6-nitrochrysene 15-19 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 45-51 11033235-7 2000 The ability of 6-NC to induce liver and lung CYP1A1 may be an important factor to consider in assessing 6-NC metabolism and toxicity in humans. 6-nitrochrysene 104-108 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 45-51