PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24710473-3	2014	In addition, whereas treatment with estrogen and progesterone was not very effective for decidualizing AMCs and MMCs, treatment with 8-Br-cAMP prompted remarkable morphological changes in these cells as well as increased expression of decidualization markers (prolactin and insulin-like growth factor binding protein-1) and attenuated expression of surface markers unique to mesenchymal stem cells.	8-Bromo Cyclic Adenosine Monophosphate	133-142	insulin like growth factor binding protein 1	Homo sapiens	274-318	
11061545-5	2000	Herein, we have investigated the effects of hypoxia and a cAMP analog, 8-bromoadenosine-3",5"-cyclic monophosphate (8-Br-cAMP), on IGFBP-1 expression in HepG2 cells, a model system for IGFBP-1 gene regulation.	8-Bromo Cyclic Adenosine Monophosphate	71-114	insulin like growth factor binding protein 1	Homo sapiens	131-138	
18815356-7	2009	Lower expression of IGFBP1 and prolactin mRNA and protein was observed in hESF from women with vs. those without endometriosis in response to 8-Br-cAMP, but not P4, suggesting a blunted response of these decidual biomarkers to activation of the PKA pathway in eutopic endometrium in women with disease.	8-Bromo Cyclic Adenosine Monophosphate	142-151	insulin like growth factor binding protein 1	Homo sapiens	20-26	
17065600-2	2007	When treated with 0.5 mM 8-Br-cAMP for 12 days, ES cells were transformed into a decidualized morphology and produced significant amounts of prolactin (PRL) and insulin-like growth factor-binding protein 1 (IGFBP1).	8-Bromo Cyclic Adenosine Monophosphate	25-34	insulin like growth factor binding protein 1	Homo sapiens	161-205	
17065600-2	2007	When treated with 0.5 mM 8-Br-cAMP for 12 days, ES cells were transformed into a decidualized morphology and produced significant amounts of prolactin (PRL) and insulin-like growth factor-binding protein 1 (IGFBP1).	8-Bromo Cyclic Adenosine Monophosphate	25-34	insulin like growth factor binding protein 1	Homo sapiens	207-213	
11061545-5	2000	Herein, we have investigated the effects of hypoxia and a cAMP analog, 8-bromoadenosine-3",5"-cyclic monophosphate (8-Br-cAMP), on IGFBP-1 expression in HepG2 cells, a model system for IGFBP-1 gene regulation.	8-Bromo Cyclic Adenosine Monophosphate	116-125	insulin like growth factor binding protein 1	Homo sapiens	131-138	
11061545-7	2000	Western ligand blotting revealed IGFBP-1 as the predominant IGFBP in HepG2-conditioned media, which increased in a dose-dependent manner after incubation with 8-Br-cAMP in normoxia and hypoxia (3-fold and 7-fold at 1 mM, respectively).	8-Bromo Cyclic Adenosine Monophosphate	159-168	insulin like growth factor binding protein 1	Homo sapiens	33-40	
11061545-9	2000	In normoxia, 8-Br-cAMP stimulated IGFBP-1 protein and mRNA levels in a dose-dependent manner (7-fold and 10-fold at 1 mM).	8-Bromo Cyclic Adenosine Monophosphate	13-22	insulin like growth factor binding protein 1	Homo sapiens	34-41	
11061545-10	2000	Hypoxia and 8-Br-cAMP showed additive stimulatory effects on IGFBP-1 protein and mRNA levels (35-fold and 50-fold at 1 mM) that were time and dose dependent.	8-Bromo Cyclic Adenosine Monophosphate	12-21	insulin like growth factor binding protein 1	Homo sapiens	61-68	
2318953-6	1990	8-Bromo-cAMP significantly increased the secretion of PRL and PP12, but not PP14, by stromal cells compared to control values.	8-Bromo Cyclic Adenosine Monophosphate	0-12	insulin like growth factor binding protein 1	Homo sapiens	62-66