PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9657065-2	1997	We have shown previously that both tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1-beta) inhibit 8-bromo-cAMP-(8-Br-cAMP)-stimulated steroidogenesis in mouse Leydig cells.	8-Bromo Cyclic Adenosine Monophosphate	118-130	interleukin 1 beta	Mus musculus	79-97	
9657065-2	1997	We have shown previously that both tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1-beta) inhibit 8-bromo-cAMP-(8-Br-cAMP)-stimulated steroidogenesis in mouse Leydig cells.	8-Bromo Cyclic Adenosine Monophosphate	118-130	interleukin 1 beta	Mus musculus	99-108	
9106264-6	1997	The addition of 8-bromo-cyclic AMP, but not 8-bromo-cyclic GMP, was found to further enhance the expression of iNOS activity induced by IL-1 beta and IFN-gamma co-stimulation.	8-Bromo Cyclic Adenosine Monophosphate	16-34	interleukin 1 beta	Mus musculus	136-145	
10708595-4	2000	Our data clearly demonstrated that in LPS-treated macrophages, cAMP elevator (CTx and 8-bromo-cAMP) could increase IL-1Ra and IL-10 gene expression, while mRNAs of IL-1alpha, IL-12, IL-6, and MIF were decreased and other cytokines like IL-1beta, and IFN-gamma did not give a definite tendency.	8-Bromo Cyclic Adenosine Monophosphate	86-98	interleukin 1 beta	Mus musculus	236-244	
10479401-9	1999	When tested with the 314 bp LIF-promoter construct, incubation of stromal cells with IL-1beta (500 U/ml) resulted in a 1.57-fold stimulation, with TNF-alpha (500 U/ml) in 2.06-fold stimulation, and with 8BrcAMP (0.5 mM) in a 3.	8-Bromo Cyclic Adenosine Monophosphate	203-210	interleukin 1 beta	Mus musculus	85-93