PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25150062-11	2014	8-Br-cAMP also blocked HDE-stimulated IL-6 and keratinocyte-derived chemokine release in precision-cut mouse lung slices (P < 0.05).	8-Bromo Cyclic Adenosine Monophosphate	0-9	interleukin 6	Mus musculus	38-42	
10708595-4	2000	Our data clearly demonstrated that in LPS-treated macrophages, cAMP elevator (CTx and 8-bromo-cAMP) could increase IL-1Ra and IL-10 gene expression, while mRNAs of IL-1alpha, IL-12, IL-6, and MIF were decreased and other cytokines like IL-1beta, and IFN-gamma did not give a definite tendency.	8-Bromo Cyclic Adenosine Monophosphate	86-98	interleukin 6	Mus musculus	182-186	
20372827-6	2010	Forskolin, a direct activator of adenylyl cyclase, or 8-bromoadenosine-3",5"-cyclic monophosphate (8bromo-cAMP), a plasma membrane-permeable cAMP analogue, markedly enhanced the TNF-alpha-induced IL-6 synthesis as well as VIP.	8-Bromo Cyclic Adenosine Monophosphate	54-97	interleukin 6	Mus musculus	196-200	
12528891-2	2002	We previously found that the cAMP-elevators (CTx and 8-Br-cAMP) inhibited IL-12, IL-la, IL-6 gene expression, but increased the transcriptional levels of IL-10 and IL-1Ra in LPS-treated murine peritoneal macrophages.	8-Bromo Cyclic Adenosine Monophosphate	53-62	interleukin 6	Mus musculus	88-92	
11459804-7	2001	IL-6 production was only slightly increased by either 8-bromo-cAMP (1 mM) or phorbol 12-myristate 13-acetate (100 nM) alone.	8-Bromo Cyclic Adenosine Monophosphate	54-66	interleukin 6	Mus musculus	0-4	
11459804-8	2001	However, IL-6 was synergistically induced in the presence of both 8-bromo-cAMP (1 mM) and phorbol 12myristate 13-acetate (100 nM).	8-Bromo Cyclic Adenosine Monophosphate	66-78	interleukin 6	Mus musculus	9-13	
8062890-8	1994	Addition to stromal cells of the soluble cAMP agonist 8-bromo-cAMP (8BrcAMP) at 0.5 to 1 mM stimulated IL-6 mRNA expression acting alone, and it was additive with IL-1 or IL-1 plus TNF-alpha in stimulating IL-6 expression.	8-Bromo Cyclic Adenosine Monophosphate	54-66	interleukin 6	Mus musculus	103-107	
8062890-8	1994	Addition to stromal cells of the soluble cAMP agonist 8-bromo-cAMP (8BrcAMP) at 0.5 to 1 mM stimulated IL-6 mRNA expression acting alone, and it was additive with IL-1 or IL-1 plus TNF-alpha in stimulating IL-6 expression.	8-Bromo Cyclic Adenosine Monophosphate	54-66	interleukin 6	Mus musculus	206-210	
8062890-8	1994	Addition to stromal cells of the soluble cAMP agonist 8-bromo-cAMP (8BrcAMP) at 0.5 to 1 mM stimulated IL-6 mRNA expression acting alone, and it was additive with IL-1 or IL-1 plus TNF-alpha in stimulating IL-6 expression.	8-Bromo Cyclic Adenosine Monophosphate	68-75	interleukin 6	Mus musculus	103-107	
8062890-8	1994	Addition to stromal cells of the soluble cAMP agonist 8-bromo-cAMP (8BrcAMP) at 0.5 to 1 mM stimulated IL-6 mRNA expression acting alone, and it was additive with IL-1 or IL-1 plus TNF-alpha in stimulating IL-6 expression.	8-Bromo Cyclic Adenosine Monophosphate	68-75	interleukin 6	Mus musculus	206-210