PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12606479-4	2003	Gonadotropin-stimulated VEGF production was mediated by cAMP-dependent protein kinase A (PKA), as evidenced by the effect of hCG being mimicked by 8Br-cAMP and being abolished in the presence of a PKA-specific inhibitor, H-89.	8-Bromo Cyclic Adenosine Monophosphate	147-155	hypertrichosis 2 (generalised, congenital)	Homo sapiens	125-128	
14636638-9	2003	The up-regulation of follistatin expression by hCG could be mimicked by all the drugs that increase the intracellular cAMP level including 8-Br-cAMP, db-cAMP, forskolin, and 3-isobutyl-1-methylxanthine (IBMX).	8-Bromo Cyclic Adenosine Monophosphate	139-148	hypertrichosis 2 (generalised, congenital)	Homo sapiens	47-50	
12050258-7	2002	In addition, these trialkyltin compounds enhanced 8-bromo-cAMP-induced hCG secretion and aromatase activity in JAR cells.	8-Bromo Cyclic Adenosine Monophosphate	50-62	hypertrichosis 2 (generalised, congenital)	Homo sapiens	71-74	
2448328-1	1988	Our previous work demonstrated that 8-bromo-cAMP promotes the secretion of both hCG and progesterone by cultured cytotrophoblasts.	8-Bromo Cyclic Adenosine Monophosphate	36-48	hypertrichosis 2 (generalised, congenital)	Homo sapiens	80-83	
9260834-12	1997	Moreover, the presence of 8Br-cAMP (0.5 or 1 mM) mimicked the stimulation by hCG.	8-Bromo Cyclic Adenosine Monophosphate	26-34	hypertrichosis 2 (generalised, congenital)	Homo sapiens	77-80	
9363223-4	1996	Both 8-Br-cGMP and 8-Br-cAMP enhanced the expression of hCG in cultured cytotrophoblasts with the differentiation of cytotrophoblasts to syncytiotrophoblasts dose-dependently.	8-Bromo Cyclic Adenosine Monophosphate	19-28	hypertrichosis 2 (generalised, congenital)	Homo sapiens	56-59	
8274420-2	1993	When the cells were exposed to 8-bromo-cAMP either in the presence or absence of hCG, the inhibitory effect of BR was not reversed.	8-Bromo Cyclic Adenosine Monophosphate	31-43	hypertrichosis 2 (generalised, congenital)	Homo sapiens	81-84	
2448328-8	1988	8-Bromo-cAMP stimulated cytotrophoblast protein kinase activity, resulting in the increased phosphorylation of a protein with a mol wt of about 70,000, and produced a marked stimulation of hCG secretion.	8-Bromo Cyclic Adenosine Monophosphate	0-12	hypertrichosis 2 (generalised, congenital)	Homo sapiens	189-192	
2579862-5	1985	Only in the presence of 8-bromo-cAMP, 8-bromo-cGMP, and cGMP + IBMX was hCG synthesized, which differs significantly in the investigated properties from hCG of the control cultures.	8-Bromo Cyclic Adenosine Monophosphate	24-36	hypertrichosis 2 (generalised, congenital)	Homo sapiens	72-75	
2579862-3	1985	The efficacy of the substances to cause an increase in the hCG medium concentration was in the following order: IBMX less than control less than 8-bromo-cGMP = 8-bromo-cAMP less than cGMP + IBMX less than cAMP + IBMX.	8-Bromo Cyclic Adenosine Monophosphate	160-172	hypertrichosis 2 (generalised, congenital)	Homo sapiens	59-62	
2846979-3	1988	Addition of 8-bromo-adenosine-3",5"-monophosphate (8-Br-cAMP), forskolin or cholera toxin (but not 8-Br-cGMP) stimulated hCG and P production by the cultivated placental cells.	8-Bromo Cyclic Adenosine Monophosphate	12-49	hypertrichosis 2 (generalised, congenital)	Homo sapiens	121-124	
2846979-3	1988	Addition of 8-bromo-adenosine-3",5"-monophosphate (8-Br-cAMP), forskolin or cholera toxin (but not 8-Br-cGMP) stimulated hCG and P production by the cultivated placental cells.	8-Bromo Cyclic Adenosine Monophosphate	51-60	hypertrichosis 2 (generalised, congenital)	Homo sapiens	121-124	
2579862-7	1985	In the presence of both 8-bromo-cAMP and 8-bromo-cGMP, microheterogeneity of hCG in isoelectric focusing was diminished and the synthesis of more acidic hCG subpopulations was favoured.	8-Bromo Cyclic Adenosine Monophosphate	24-36	hypertrichosis 2 (generalised, congenital)	Homo sapiens	77-80	
2579862-7	1985	In the presence of both 8-bromo-cAMP and 8-bromo-cGMP, microheterogeneity of hCG in isoelectric focusing was diminished and the synthesis of more acidic hCG subpopulations was favoured.	8-Bromo Cyclic Adenosine Monophosphate	24-36	hypertrichosis 2 (generalised, congenital)	Homo sapiens	153-156	
3974230-1	1985	A collagenase dispersed cell suspension from PMSG-hCG primed immature rats responded to exogenously added hCG, cholera enteroxin, prolactin, and 8-Bromocyclic-AMP with increase in progesterone production in a dose dependent manner, and this stimulation was augmented by the plasma lipoprotein fractions hHDL and hLDL.	8-Bromo Cyclic Adenosine Monophosphate	145-162	hypertrichosis 2 (generalised, congenital)	Homo sapiens	50-53