PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14636638-9 2003 The up-regulation of follistatin expression by hCG could be mimicked by all the drugs that increase the intracellular cAMP level including 8-Br-cAMP, db-cAMP, forskolin, and 3-isobutyl-1-methylxanthine (IBMX). 8-Bromo Cyclic Adenosine Monophosphate 139-148 hypertrichosis 2 (generalised, congenital) Homo sapiens 47-50 12050258-7 2002 In addition, these trialkyltin compounds enhanced 8-bromo-cAMP-induced hCG secretion and aromatase activity in JAR cells. 8-Bromo Cyclic Adenosine Monophosphate 50-62 hypertrichosis 2 (generalised, congenital) Homo sapiens 71-74 12606479-4 2003 Gonadotropin-stimulated VEGF production was mediated by cAMP-dependent protein kinase A (PKA), as evidenced by the effect of hCG being mimicked by 8Br-cAMP and being abolished in the presence of a PKA-specific inhibitor, H-89. 8-Bromo Cyclic Adenosine Monophosphate 147-155 hypertrichosis 2 (generalised, congenital) Homo sapiens 125-128 9363223-4 1996 Both 8-Br-cGMP and 8-Br-cAMP enhanced the expression of hCG in cultured cytotrophoblasts with the differentiation of cytotrophoblasts to syncytiotrophoblasts dose-dependently. 8-Bromo Cyclic Adenosine Monophosphate 19-28 hypertrichosis 2 (generalised, congenital) Homo sapiens 56-59 9260834-12 1997 Moreover, the presence of 8Br-cAMP (0.5 or 1 mM) mimicked the stimulation by hCG. 8-Bromo Cyclic Adenosine Monophosphate 26-34 hypertrichosis 2 (generalised, congenital) Homo sapiens 77-80 2846979-3 1988 Addition of 8-bromo-adenosine-3",5"-monophosphate (8-Br-cAMP), forskolin or cholera toxin (but not 8-Br-cGMP) stimulated hCG and P production by the cultivated placental cells. 8-Bromo Cyclic Adenosine Monophosphate 12-49 hypertrichosis 2 (generalised, congenital) Homo sapiens 121-124 2448328-1 1988 Our previous work demonstrated that 8-bromo-cAMP promotes the secretion of both hCG and progesterone by cultured cytotrophoblasts. 8-Bromo Cyclic Adenosine Monophosphate 36-48 hypertrichosis 2 (generalised, congenital) Homo sapiens 80-83 2448328-8 1988 8-Bromo-cAMP stimulated cytotrophoblast protein kinase activity, resulting in the increased phosphorylation of a protein with a mol wt of about 70,000, and produced a marked stimulation of hCG secretion. 8-Bromo Cyclic Adenosine Monophosphate 0-12 hypertrichosis 2 (generalised, congenital) Homo sapiens 189-192 8274420-2 1993 When the cells were exposed to 8-bromo-cAMP either in the presence or absence of hCG, the inhibitory effect of BR was not reversed. 8-Bromo Cyclic Adenosine Monophosphate 31-43 hypertrichosis 2 (generalised, congenital) Homo sapiens 81-84 2846979-3 1988 Addition of 8-bromo-adenosine-3",5"-monophosphate (8-Br-cAMP), forskolin or cholera toxin (but not 8-Br-cGMP) stimulated hCG and P production by the cultivated placental cells. 8-Bromo Cyclic Adenosine Monophosphate 51-60 hypertrichosis 2 (generalised, congenital) Homo sapiens 121-124 3974230-1 1985 A collagenase dispersed cell suspension from PMSG-hCG primed immature rats responded to exogenously added hCG, cholera enteroxin, prolactin, and 8-Bromocyclic-AMP with increase in progesterone production in a dose dependent manner, and this stimulation was augmented by the plasma lipoprotein fractions hHDL and hLDL. 8-Bromo Cyclic Adenosine Monophosphate 145-162 hypertrichosis 2 (generalised, congenital) Homo sapiens 50-53 2579862-5 1985 Only in the presence of 8-bromo-cAMP, 8-bromo-cGMP, and cGMP + IBMX was hCG synthesized, which differs significantly in the investigated properties from hCG of the control cultures. 8-Bromo Cyclic Adenosine Monophosphate 24-36 hypertrichosis 2 (generalised, congenital) Homo sapiens 72-75 2579862-7 1985 In the presence of both 8-bromo-cAMP and 8-bromo-cGMP, microheterogeneity of hCG in isoelectric focusing was diminished and the synthesis of more acidic hCG subpopulations was favoured. 8-Bromo Cyclic Adenosine Monophosphate 24-36 hypertrichosis 2 (generalised, congenital) Homo sapiens 77-80 2579862-7 1985 In the presence of both 8-bromo-cAMP and 8-bromo-cGMP, microheterogeneity of hCG in isoelectric focusing was diminished and the synthesis of more acidic hCG subpopulations was favoured. 8-Bromo Cyclic Adenosine Monophosphate 24-36 hypertrichosis 2 (generalised, congenital) Homo sapiens 153-156 2579862-3 1985 The efficacy of the substances to cause an increase in the hCG medium concentration was in the following order: IBMX less than control less than 8-bromo-cGMP = 8-bromo-cAMP less than cGMP + IBMX less than cAMP + IBMX. 8-Bromo Cyclic Adenosine Monophosphate 160-172 hypertrichosis 2 (generalised, congenital) Homo sapiens 59-62