PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11397723-5	2001	Because the expression of TF and PAI-1 mRNA induced by Ang II was attenuated by the increase of intracellular concentrations of cAMP by forskolin and 8-bromo-cAMP and because AM increased the intracellular level of cAMP in rat aortic endothelial cells, it was indicated that the inhibitory effect of AM on the expressions of TF and PAI-1 was mainly mediated by the cAMP-dependent signal transduction.	8-Bromo Cyclic Adenosine Monophosphate	150-162	serpin family E member 1	Rattus norvegicus	33-38	
9873066-2	1999	Incubation of HTC rat hepatoma cells with the cyclic nucleotide analogue 8-bromo-cAMP results in a 3-fold increase in the rate of degradation of type-1 plasminogen activator-inhibitor (PAI-1) mRNA.	8-Bromo Cyclic Adenosine Monophosphate	73-85	serpin family E member 1	Rattus norvegicus	185-190	
11001948-1	2001	Incubation of HTC rat hepatoma cells with 8-bromo-cAMP results in a 3-fold increase in the rate of degradation of type-1 plasminogen activator inhibitor (PAI-1) mRNA.	8-Bromo Cyclic Adenosine Monophosphate	42-54	serpin family E member 1	Rattus norvegicus	154-159	
9603932-3	1998	Incubation of HTC rat hepatoma cells with the cyclic nucleotide analogue, 8-bromo-cAMP, causes a dramatic increase in tissue-type plasminogen activator activity secondary to a 90% decrease in PAI-1 mRNA.	8-Bromo Cyclic Adenosine Monophosphate	74-86	serpin family E member 1	Rattus norvegicus	192-197	
9603932-4	1998	Although 8-bromo-cAMP causes a modest decrease in PAI-1 transcription, regulation is primarily the result of a 3-fold increase in the rate of PAI-1 mRNA degradation.	8-Bromo Cyclic Adenosine Monophosphate	9-21	serpin family E member 1	Rattus norvegicus	50-55	
9603932-4	1998	Although 8-bromo-cAMP causes a modest decrease in PAI-1 transcription, regulation is primarily the result of a 3-fold increase in the rate of PAI-1 mRNA degradation.	8-Bromo Cyclic Adenosine Monophosphate	9-21	serpin family E member 1	Rattus norvegicus	142-147	
8138587-5	1994	While 8-bromo-cAMP reduced both constitutive and transforming growth factor-beta-induced p52(PAI-1) synthesis by > 50%, no such inhibition was evident in short-term (4 h) CD-stimulated cultures.	8-Bromo Cyclic Adenosine Monophosphate	6-18	serpin family E member 1	Rattus norvegicus	93-98	
8138587-6	1994	Long-term (24 h) exposure of NRK/CD cells to 8-bromo-cAMP did result in an approximately 34% reduction in stimulated p52(PAI-1) expression, however, levels expressed by NRK/CD+cAMP populations remained markedly elevated relative to control values.	8-Bromo Cyclic Adenosine Monophosphate	45-57	serpin family E member 1	Rattus norvegicus	121-126	
1738371-3	1992	The cyclic nucleotide analog 8-bromo-cAMP (cA) causes a greater than 50-fold increase in PA activity, the result of a 90% decrease in PAI-1 and a sustained 2-fold increase in tPA mRNA accumulation.	8-Bromo Cyclic Adenosine Monophosphate	29-41	serpin family E member 1	Rattus norvegicus	134-139