PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9291190-6	1997	The effect of angiotensin II upon DNA and protein synthesis was inhibited by 8-bromo-cAMP and losartan but not by PD 123319, indicating that the responses are mediated via the AT1 receptor and dependent upon the inhibition of adenylate cyclase.	8-Bromo Cyclic Adenosine Monophosphate	77-89	angiotensinogen	Homo sapiens	14-28	
15711021-4	2004	A 24 h exposure to the cAMP analog 8Br-cAMP resulted in significant increases in ATG mRNA levels (+176+/-60%) and protein secretion (+40+/-27%).	8-Bromo Cyclic Adenosine Monophosphate	35-43	angiotensinogen	Homo sapiens	81-84	
15711021-5	2004	The ability of 8Br-cAMP to promote ATG gene expression was unaltered by H89, a protein kinase A inhibitor, because H89 per se was found to stimulate ATG mRNA levels and protein secretion.	8-Bromo Cyclic Adenosine Monophosphate	15-23	angiotensinogen	Homo sapiens	35-38	
11108138-5	2000	The addition of a combination of isoproterenol and iodoclonidine or a combination of 8-Bromo-cAMP (8-Br-cAMP) and phorbol 12-myristate (PMA) synergistically stimulated the expression of the ANG-GH fusion gene as compared to the addition of isoproterenol, iodoclonidine, 8-Br-cAMP or PMA alone.	8-Bromo Cyclic Adenosine Monophosphate	85-97	angiotensinogen	Homo sapiens	190-193	
11108138-5	2000	The addition of a combination of isoproterenol and iodoclonidine or a combination of 8-Bromo-cAMP (8-Br-cAMP) and phorbol 12-myristate (PMA) synergistically stimulated the expression of the ANG-GH fusion gene as compared to the addition of isoproterenol, iodoclonidine, 8-Br-cAMP or PMA alone.	8-Bromo Cyclic Adenosine Monophosphate	99-108	angiotensinogen	Homo sapiens	190-193	
11108138-6	2000	Furthermore, the addition of NE, 8-Br-cAMP or PMA stimulated the expression of pOGH (rANG N-806/-779/-53/+18), a fusion gene containing the putative cAMP responsive element (CRE, ANG N-806/-779) upstream of the ANG promoter (ANG N-53/+18) in OK cells, but had no effect on the expression of fusion genes containing the mutant of the CRE.	8-Bromo Cyclic Adenosine Monophosphate	33-42	angiotensinogen	Homo sapiens	86-89	
9180634-9	1997	8-Bromo-cAMP, a cAMP analogue, and forskolin, an activator of adenylate cyclase, inhibited the Ang II-induced SMC migration.	8-Bromo Cyclic Adenosine Monophosphate	0-12	angiotensinogen	Homo sapiens	95-101	
2547768-7	1989	This change in the pattern of the higher inositol phosphate response to AII was manifested within 2 h after exposure to ACTH, and was mimicked by treatment with 8-bromo cyclic AMP or forskolin.	8-Bromo Cyclic Adenosine Monophosphate	161-179	angiotensinogen	Homo sapiens	72-75	
2833494-9	1988	8-bromo-cAMP bypasses the inhibitory effect of forskolin as well as AII.	8-Bromo Cyclic Adenosine Monophosphate	0-12	angiotensinogen	Homo sapiens	68-71	
7996791-0	1994	Isoproterenol and 8-bromo-cyclic adenosine monophosphate stimulate the expression of the angiotensinogen gene in opossum kidney cells.	8-Bromo Cyclic Adenosine Monophosphate	18-56	angiotensinogen	Homo sapiens	89-104	
7996791-7	1994	In contrast, the addition of 8-bromo-cAMP (8-Br-cAMP) and forskolin stimulated the expression of pOGH (ANG N-1498/+18) in a dose-dependent manner.	8-Bromo Cyclic Adenosine Monophosphate	29-41	angiotensinogen	Homo sapiens	103-106	
7996791-7	1994	In contrast, the addition of 8-bromo-cAMP (8-Br-cAMP) and forskolin stimulated the expression of pOGH (ANG N-1498/+18) in a dose-dependent manner.	8-Bromo Cyclic Adenosine Monophosphate	43-52	angiotensinogen	Homo sapiens	103-106	
7996791-10	1994	Furthermore, the stimulatory effect of isoproterenol and 8-Br-cAMP on the expression of the pOGH (ANG N-1498/+18) was inhibited by the presence of Rp-cAMP (an inhibitor of cAMP-dependent protein kinase A I and II).	8-Bromo Cyclic Adenosine Monophosphate	57-66	angiotensinogen	Homo sapiens	98-101