PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15537869-7	2005	Indeed, PDE3 inhibitor cilostamide caused potentiation of 8-bromo-cAMP-elicited elevations of Cx43 expression that is similar to the effect of SNAP, and an elevation of intracellular cAMP was detected in SNAP-treated cells.	8-Bromo Cyclic Adenosine Monophosphate	58-70	gap junction protein alpha 1	Homo sapiens	94-98	
15605363-5	2005	8-br-cAMP, known to initiate the differentiation process in cancer cells, was used to examine changes in Cx43 localization and expression via immunocytochemistry, Western blot analysis, and flow cytometry.	8-Bromo Cyclic Adenosine Monophosphate	0-9	gap junction protein alpha 1	Homo sapiens	105-109	
15605363-8	2005	The use of a PKA inhibitor further confirmed the specificity of 8-br-cAMP and forskolin"s effect on Cx43.	8-Bromo Cyclic Adenosine Monophosphate	64-73	gap junction protein alpha 1	Homo sapiens	100-104	
12349910-3	2002	Using a combination of in vivo metabolic labeling and in vitro phosphorylation of recombinant protein and synthetic peptides, we now find that connexin43 is a relatively poor substrate for purified protein kinase A compared to protein kinase C, but that phosphorylation can be accelerated by 8-Br-cAMP (8-bromoadenosine 3",5"-cyclic monophosphate) which also enhances connexin43 synthesis but at a much slower rate than phosphorylation.	8-Bromo Cyclic Adenosine Monophosphate	292-301	gap junction protein alpha 1	Homo sapiens	143-153	
12193939-4	2002	RESULTS: Nitric oxide and 8-bromo-cAMP reduced the level of connexin 43 expression, and 8-bromo-cGMP had no effect.	8-Bromo Cyclic Adenosine Monophosphate	26-38	gap junction protein alpha 1	Homo sapiens	60-71	
8828851-9	1996	Thus, 8-bromo-cAMP increased Cx43-containing cell surface gap junctional plaques and up-regulated junctional communication but attenuated the oxytocin-induced [Ca2+]i response.	8-Bromo Cyclic Adenosine Monophosphate	6-18	gap junction protein alpha 1	Homo sapiens	29-33	
11502095-6	2001	Cells maintained in CD in the presence of 8-bromoadenosine 3":5"-cyclic monophosphate exhibited restoration of Cx43 at the plasma membrane and increased GJIC and inhibition of apoptosis.	8-Bromo Cyclic Adenosine Monophosphate	42-85	gap junction protein alpha 1	Homo sapiens	111-115	
9918203-5	1999	We used 8-bromo-cyclic-AMP to induce Cx43 and GJIC.	8-Bromo Cyclic Adenosine Monophosphate	8-26	gap junction protein alpha 1	Homo sapiens	37-41	
8381593-8	1993	At 6 h of treatment, both TPA- and 8-BrcAMP-treated cultures showed markedly elevated levels of connexin43, whereas at 24 h, the level of connexin43 in TPA-treated cultures had returned to control levels.	8-Bromo Cyclic Adenosine Monophosphate	35-43	gap junction protein alpha 1	Homo sapiens	96-106	
8381593-8	1993	At 6 h of treatment, both TPA- and 8-BrcAMP-treated cultures showed markedly elevated levels of connexin43, whereas at 24 h, the level of connexin43 in TPA-treated cultures had returned to control levels.	8-Bromo Cyclic Adenosine Monophosphate	35-43	gap junction protein alpha 1	Homo sapiens	138-148	
28559397-7	2017	Inhibition of PKA, but not PKG (protein kinase G), abrogated the 8-Br-cAMP-stimulated increase in nonphosphorylated S365 and total Cx43 phosphorylation and inhibited S368 below basal levels, whereas inhibition of PKG blocked (P<0.05) the 8-bromo-cGMP-stimulated rises in nonphosphorylated S365, total Cx43, and S368 phosphorylation levels in P-UAECs.	8-Bromo Cyclic Adenosine Monophosphate	65-74	gap junction protein alpha 1	Homo sapiens	131-135	
28559397-7	2017	Inhibition of PKA, but not PKG (protein kinase G), abrogated the 8-Br-cAMP-stimulated increase in nonphosphorylated S365 and total Cx43 phosphorylation and inhibited S368 below basal levels, whereas inhibition of PKG blocked (P<0.05) the 8-bromo-cGMP-stimulated rises in nonphosphorylated S365, total Cx43, and S368 phosphorylation levels in P-UAECs.	8-Bromo Cyclic Adenosine Monophosphate	65-74	gap junction protein alpha 1	Homo sapiens	304-308	
28559397-9	2017	Thus, in P-UAECs, only 8-Br-cAMP and not 8-Br-cGMP effectively enhances nonphosphorylated S365 and total Cx43 expression that correspondingly reduces S368 phosphorylation, allowing increased GJ communication.	8-Bromo Cyclic Adenosine Monophosphate	23-32	gap junction protein alpha 1	Homo sapiens	105-109