PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17427962-12	2007	We further demonstrated that the adenylate cyclase activator forskolin and the cAMP anologue 8-bromo-cAMP mimicked the effects of PGE2 on VEGF secretion in PC-3 cells.	8-Bromo Cyclic Adenosine Monophosphate	93-105	vascular endothelial growth factor A	Homo sapiens	138-142	
16809546-6	2006	Addition of 8bromo-cAMP or adrenomedullin (AM), an endogenous ligand-elevating cAMP, enhanced VEGF-induced EC differentiation.	8-Bromo Cyclic Adenosine Monophosphate	12-23	vascular endothelial growth factor A	Homo sapiens	94-98	
16809546-7	2006	Whereas VEGF alone mainly induced venous ECs, 8bromo-cAMP (or AM) with VEGF supported substantial induction of arterial ECs.	8-Bromo Cyclic Adenosine Monophosphate	46-57	vascular endothelial growth factor A	Homo sapiens	71-75	
16484616-8	2006	Treatment of endothelial cells with Rp-8-Br-cAMP, an inhibitor of PKA, or small interference RNA to PKA was able to reverse the inhibitory effects of IP-10 on VEGF-mediated tube formation and motility.	8-Bromo Cyclic Adenosine Monophosphate	39-48	vascular endothelial growth factor A	Homo sapiens	159-163	
15944267-8	2005	CRH-stimulated VEGF production was mediated through activation of adenylate cyclase and increased cAMP, as evidenced by the fact that the effect of CRH was mimicked by the direct adenylate cyclase activator forskolin and the cell-permeable cAMP analog 8-bromo-cAMP, whereas it was abolished by the adenylate cyclase inhibitor SQ22536.	8-Bromo Cyclic Adenosine Monophosphate	252-264	vascular endothelial growth factor A	Homo sapiens	15-19	
12821125-6	2003	Whereas PGE(2) stimulated intracellular cAMP formation in COX-2 positive and negative cells, 8-bromo cAMP stimulated VEGF production only in COX-2 expressing cells.	8-Bromo Cyclic Adenosine Monophosphate	93-105	vascular endothelial growth factor A	Homo sapiens	117-121	
9361190-5	1997	Both VEGF- and bFGF-induced Raf-1 activity are blocked in the presence of forskolin or 8-bromo-cAMP by 80%.	8-Bromo Cyclic Adenosine Monophosphate	87-99	vascular endothelial growth factor A	Homo sapiens	5-10	
12010778-7	2002	8-Bromo cyclic AMP and dibutyryl cyclic AMP, cyclic AMP analogues, mimicked the effects of PGE(2) on IL-6, M-CSF, and VEGF production by OA fibroblasts.	8-Bromo Cyclic Adenosine Monophosphate	0-18	vascular endothelial growth factor A	Homo sapiens	118-122	
10965822-5	2000	8-bromo-cAMP and cholera toxin also increased VEGF production by H-Mac.	8-Bromo Cyclic Adenosine Monophosphate	0-12	vascular endothelial growth factor A	Homo sapiens	46-50