PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15209353-0 2004 Dehydrocostus lactone enhances tumor necrosis factor-alpha-induced apoptosis of human leukemia HL-60 cells. Lactones 14-21 tumor necrosis factor Homo sapiens 31-58 12970407-4 2003 By varying the alkyl side chains of these synthetic DAG lactones, it was possible to maximize their potency and ability to render latently infected T cells sensitive to killing by an anti-HIV-1 immunotoxin while minimizing the side effects of CD4 and CXCR4 downregulation and tumor necrosis factor alpha upregulation. Lactones 56-64 tumor necrosis factor Homo sapiens 276-303