PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9578548-8	1998	X-ray crystal structures of alpha-thrombin/GR133686 (3.0 A resolution) and alpha-thrombin/GR133487 (2.2 A resolution) complexes showed continuous electron density between Ser195 and the ring-opened lactone carbonyl, demonstrating acyl-enzyme formation.	Lactones	198-205	coagulation factor II, thrombin	Homo sapiens	34-42	
9578548-8	1998	X-ray crystal structures of alpha-thrombin/GR133686 (3.0 A resolution) and alpha-thrombin/GR133487 (2.2 A resolution) complexes showed continuous electron density between Ser195 and the ring-opened lactone carbonyl, demonstrating acyl-enzyme formation.	Lactones	198-205	coagulation factor II, thrombin	Homo sapiens	81-89	
15152989-1	2004	The concise synthesis of a potent thrombin inhibitor was accomplished by a mild lactone aminolysis between an orthogonally protected bis-benzylic amine and a diastereomerically pure lactone.	Lactones	80-87	coagulation factor II, thrombin	Homo sapiens	34-42	
15152989-1	2004	The concise synthesis of a potent thrombin inhibitor was accomplished by a mild lactone aminolysis between an orthogonally protected bis-benzylic amine and a diastereomerically pure lactone.	Lactones	182-189	coagulation factor II, thrombin	Homo sapiens	34-42