PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31999126-1	2020	alpha-Bromolactones bearing a substituent in the beta-position undergo a highly trans-diastereoselective arylation with arylzinc chlorides in the presence of 10-20% CoCl2 and 10-20% PPh3 in THF under mild conditions (25  C, 16 h) leading to optically enriched alpha-arylated lactones and protected aldol products (99% ee) in 52-96% yield.	Lactones	11-19	caveolin 1	Homo sapiens	182-186