PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18707088-4	2008	Some of the DAG-lactones obtained show selective binding to RasGRP3 as compared to PKCalpha by more than 2 orders of magnitude and possess subnanomolar affinities.	Lactones	16-24	protein kinase C alpha	Homo sapiens	83-91	
19406749-6	2009	Expression of a phosphorylation-resistant mutant (S165N-alpha6-tubulin) resulted in suppression of MCF-10A cell motility stimulated either by expression of PKCalpha or by treatment with PKCalpha-selective activator diacylglycerol-lactone.	Lactones	230-237	protein kinase C alpha	Homo sapiens	186-194	
17284021-2	2007	Modulation of membrane translocation of protein kinase C (PKC) isozymes alpha and delta by diacylglycerol lactones (DAG-lactones) containing rigid-rod acyl groups.	Lactones	106-114	protein kinase C alpha	Homo sapiens	58-61	
11584014-0	2002	Diacylglycerol (DAG)-lactones, a new class of protein kinase C (PKC) agonists, induce apoptosis in LNCaP prostate cancer cells by selective activation of PKCalpha.	Lactones	21-29	protein kinase C alpha	Homo sapiens	64-67	
11584014-0	2002	Diacylglycerol (DAG)-lactones, a new class of protein kinase C (PKC) agonists, induce apoptosis in LNCaP prostate cancer cells by selective activation of PKCalpha.	Lactones	21-29	protein kinase C alpha	Homo sapiens	154-162	
11584014-2	2002	In this study we evaluate the effect of a novel class of PKC ligands, the diacylglycerol (DAG)-lactones, as inducers of apoptosis in LNCaP cells.	Lactones	95-103	protein kinase C alpha	Homo sapiens	57-60	
10518540-7	1999	The different DAG lactones show some selectivity for this novel receptor compared with PKCalpha.	Lactones	18-26	protein kinase C alpha	Homo sapiens	87-95	
28671468-8	2017	For the intact PKCalpha and PKCdelta, the shortest DAG-lactone dimer had similar affinity to the monomer and affinity decreased progressively up to the 16-carbon linker.	Lactones	55-62	protein kinase C alpha	Homo sapiens	15-23