PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10704251-3	2000	Because activation of NF-kappaB is involved in the regulation of the chemokine interleukin 8 (IL-8), we hypothesized that the sesquiterpene lactones, isohelenin and parthenolide, would inhibit IL-8 gene expression in cultured human respiratory epithelium.	Lactones	140-148	nuclear factor kappa B subunit 1	Homo sapiens	22-31	
15183076-5	2004	In this contribution we analyzed the mechanism of the sesquiterpene lactone-mediated inhibition using different cell systems, and showed that in all the cell lines analyzed, SLs inhibited both NF-kappaB binding and the IkappaB-kinase, but that the former played a more preponderant role in the inhibition.	Lactones	68-75	nuclear factor kappa B subunit 1	Homo sapiens	193-202	
34021233-2	2021	Previously we reported that the plant-derived steroidal lactone Withaferin A (WA) can protect islet grafts by inhibiting nuclear factor-kappa B (NF-kappaB).	Lactones	56-63	nuclear factor kappa B subunit 1	Homo sapiens	121-143	
34021233-2	2021	Previously we reported that the plant-derived steroidal lactone Withaferin A (WA) can protect islet grafts by inhibiting nuclear factor-kappa B (NF-kappaB).	Lactones	56-63	nuclear factor kappa B subunit 1	Homo sapiens	145-154	
30999647-0	2019	Dehydrocostus Lactone Suppresses LPS-induced Acute Lung Injury and Macrophage Activation through NF-kappaB Signaling Pathway Mediated by p38 MAPK and Akt.	Lactones	14-21	nuclear factor kappa B subunit 1	Homo sapiens	97-106