PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12970407-4 2003 By varying the alkyl side chains of these synthetic DAG lactones, it was possible to maximize their potency and ability to render latently infected T cells sensitive to killing by an anti-HIV-1 immunotoxin while minimizing the side effects of CD4 and CXCR4 downregulation and tumor necrosis factor alpha upregulation. Lactones 56-64 CD4 molecule Homo sapiens 243-246 27626296-0 2016 GM-3 Lactone Mimetic Interacts with CD4 and HIV-1 Env Proteins, Hampering HIV-1 Infection without Inducing a Histopathological Alteration. Lactones 5-12 CD4 molecule Homo sapiens 36-39