PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20137986-2 2010 Hypersensitivity of CD8(+) T cells to IL-2 was dependent on a low-level TCR signal, associated with high expression of CD5 and GM1, a marker for lipid rafts, and was abolished by disruption of lipid rafts. G(M1) Ganglioside 127-130 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 72-75 20137986-5 2010 Thus, TCR contact with antigen upregulates GM1 and amplifies responsiveness of naive CD8(+) T cells to IL-2, thereby making the cells highly sensitive to exogenous IL-2 from CD4(+) T helper cells. G(M1) Ganglioside 43-46 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 6-9 12667680-3 2003 Herein, we describe a strategy for detecting fine alterations in the amount and distribution of glycosphingolipid (GM1) lipid rafts, and in the formation of GM1-TCR complexes in detergent-insoluble and -soluble compartments of the T cell membrane from a relative low number of cells. G(M1) Ganglioside 157-160 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 161-164 12884293-7 2003 Our evidence that Vav overexpression counteracted both the Nef-induced decrease of GM1 expression and the inhibition of NF-AT activity, suggests a novel mechanism by which Nef may interfere with TCR-mediated activation through the modulation of intracellular trafficking and clustering of GM1-enriched microdomains at the cell surface. G(M1) Ganglioside 83-86 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 195-198 12884293-7 2003 Our evidence that Vav overexpression counteracted both the Nef-induced decrease of GM1 expression and the inhibition of NF-AT activity, suggests a novel mechanism by which Nef may interfere with TCR-mediated activation through the modulation of intracellular trafficking and clustering of GM1-enriched microdomains at the cell surface. G(M1) Ganglioside 289-292 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 195-198 12667680-4 2003 Using this strategy, we found that the GM1 moiety was physically associated with TCR in both detergent-insoluble and -soluble fractions. G(M1) Ganglioside 39-42 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 81-84 12142032-9 2002 TCR clustering led only to a partial colocalization of TCRs with raft GSL, ganglioside GM1, and a complete colocalization of CP with TCRs. G(M1) Ganglioside 75-90 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 0-3 12239168-8 2002 The ganglioside GM1, a marker of rafts, was augmented in TCR-stimulated but not IL-7-stimulated T lymphocytes, and disruption of rafts inhibited gp120-induced signaling. G(M1) Ganglioside 16-19 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 57-60