PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20237277-5	2010	Administration of GM1 restores ganglioside levels in HD cells and promotes activation of AKT and phosphorylation of mutant Htt, leading to decreased mutant Htt toxicity and increased survival of HD cells.	G(M1) Ganglioside	18-21	AKT serine/threonine kinase 1	Homo sapiens	89-92	
25039425-6	2014	The increase in GM1 expression induced by leptin was inhibited after pre-treatment with inhibitors of phosphatidylinositol 3-kinase (LY294002), Akt (triciribine) and the mammalian target of rapamycin (i.e. rapamycin), but not by an inhibitor of extracellular signal-regulated kinase (PD98059).	G(M1) Ganglioside	16-19	AKT serine/threonine kinase 1	Homo sapiens	144-147	
25039425-10	2014	These results suggest that leptin significantly inhibits Abeta assembly by decreasing GM1 expression in DRMs of the neuronal surface through the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway.	G(M1) Ganglioside	86-89	AKT serine/threonine kinase 1	Homo sapiens	175-178