PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7986393-6 1994 The number and morphologic change of SH-SY5Y cells were evaluated in the serum free medium added GM1 ganglioside with insulin or PDGF. G(M1) Ganglioside 97-112 insulin Homo sapiens 118-125 12974752-5 2003 Mechanistically we found that uptake or transport of insulin-CTB conjugates in the gut occurs at least partially via binding to GM-1, which would explain the enhanced clinical efficacy. G(M1) Ganglioside 128-132 insulin Homo sapiens 53-60 9788349-4 1998 Transgenic potato tubers produced 0.1% of total soluble protein as the pentameric CTB-insulin fusion, which retained GM1-ganglioside binding affinity and native antigenicity of both CTB and insulin. G(M1) Ganglioside 117-132 insulin Homo sapiens 86-93 31013778-6 2019 First, it was shown that increased GM1 levels associated with aging/senescence contribute to insulin resistance in human aortic endothelial cells (HAECs). G(M1) Ganglioside 35-38 insulin Homo sapiens 93-100 20504586-6 1990 In the same animal model peripheral, but not central, administration of GM1 reduced the hypoglycemia-induced increase of cerebral blood flow and increased the survival time observed after the insulin injection. G(M1) Ganglioside 72-75 insulin Homo sapiens 192-199 26338710-0 2015 Ganglioside GM1 Contributes to the State of Insulin Resistance in Senescent Human Arterial Endothelial Cells. G(M1) Ganglioside 12-15 insulin Homo sapiens 44-51 29464018-0 2018 Ganglioside GM1 contributes to extracellular/intracellular regulation of insulin resistance, impairment of insulin signaling and down-stream eNOS activation, in human aortic endothelial cells after short- or long-term exposure to TNFalpha. G(M1) Ganglioside 12-15 insulin Homo sapiens 73-80 29464018-8 2018 Our data suggest that GM1 is a key player in the induction of vascular insulin resistance after short- or long-term exposure to TNFalpha and is a good extracellular target for prevention and cure of vascular diseases. G(M1) Ganglioside 22-25 insulin Homo sapiens 71-78 26338710-10 2015 GM1 may be an attractive target for the detection, prevention, and therapy of insulin resistance and related vascular diseases, particularly in older people. G(M1) Ganglioside 0-3 insulin Homo sapiens 78-85