PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18581052-0 2008 Co-localization of galectin-1 with GM1 ganglioside in the course of its clathrin- and raft-dependent endocytosis. G(M1) Ganglioside 35-50 galectin 1 Homo sapiens 19-29 11451961-1 2001 The cell density-dependent growth inhibition of human SK-N-MC neuroblastoma cells is initiated by increased ganglioside sialidase activity leading to elevated cell surface presentation of ganglioside GM1, a ligand of galectin-1. G(M1) Ganglioside 200-203 galectin 1 Homo sapiens 217-227 9556610-0 1998 Galectin-1 is a major receptor for ganglioside GM1, a product of the growth-controlling activity of a cell surface ganglioside sialidase, on human neuroblastoma cells in culture. G(M1) Ganglioside 47-50 galectin 1 Homo sapiens 0-10 9556610-5 1998 Presence during cell culture of the sialidase inhibitor 2-deoxy-2,3-dehydro-N-acetylneuraminic acid or of the GM1-binding cholera toxin B subunit effected a decrease of the presentation of galectin-1 ligands by 30-50%. G(M1) Ganglioside 110-113 galectin 1 Homo sapiens 189-199 9556610-6 1998 The assumption that GM1 is a major ligand for galectin-1 was reinforced by the correlation between the number of carbohydrate-dependent 125I-iodinated GM1-neoganglioprotein binding sites and the amount of immunoreactive surface galectin-1, the marked sensitivity of probe binding to the presence of anti-galectin-1 antibody, and the inhibition of cell adhesion to surface-immobilized GM1 by the antibody. G(M1) Ganglioside 20-23 galectin 1 Homo sapiens 46-56 9556610-6 1998 The assumption that GM1 is a major ligand for galectin-1 was reinforced by the correlation between the number of carbohydrate-dependent 125I-iodinated GM1-neoganglioprotein binding sites and the amount of immunoreactive surface galectin-1, the marked sensitivity of probe binding to the presence of anti-galectin-1 antibody, and the inhibition of cell adhesion to surface-immobilized GM1 by the antibody. G(M1) Ganglioside 20-23 galectin 1 Homo sapiens 228-238 9556610-6 1998 The assumption that GM1 is a major ligand for galectin-1 was reinforced by the correlation between the number of carbohydrate-dependent 125I-iodinated GM1-neoganglioprotein binding sites and the amount of immunoreactive surface galectin-1, the marked sensitivity of probe binding to the presence of anti-galectin-1 antibody, and the inhibition of cell adhesion to surface-immobilized GM1 by the antibody. G(M1) Ganglioside 20-23 galectin 1 Homo sapiens 228-238 9556610-6 1998 The assumption that GM1 is a major ligand for galectin-1 was reinforced by the correlation between the number of carbohydrate-dependent 125I-iodinated GM1-neoganglioprotein binding sites and the amount of immunoreactive surface galectin-1, the marked sensitivity of probe binding to the presence of anti-galectin-1 antibody, and the inhibition of cell adhesion to surface-immobilized GM1 by the antibody. G(M1) Ganglioside 151-154 galectin 1 Homo sapiens 46-56 9556610-7 1998 The results open the possibility that the carbohydrate-dependent interaction between ganglioside GM1 and galectin-1 may relay sialidase-dependent alterations in this cell system. G(M1) Ganglioside 85-100 galectin 1 Homo sapiens 105-115 29747818-9 2018 The GD1a-to-GM1 "editing" is recognized by such lectins, for example, myelin-associated glycoprotein (siglec-4) losing affinity and galectin-1 gaining reactivity, and then translated into postbinding signaling. G(M1) Ganglioside 12-15 galectin 1 Homo sapiens 132-142 26542007-1 2015 The specific interaction of ganglioside GM1 with the homodimeric (prototype) endogenous lectin galectin-1 triggers growth regulation in tumor and activated effector T cells. G(M1) Ganglioside 40-43 galectin 1 Homo sapiens 95-105 24231767-0 2014 GM1 controlled lateral segregation of tyrosine kinase Lck predispose T-cells to cell-derived galectin-1-induced apoptosis. G(M1) Ganglioside 0-3 galectin 1 Homo sapiens 93-103 24231767-8 2014 Level of the Gal-1-binding glycolipid GM1 ganglioside also essentially regulated Lck localization. G(M1) Ganglioside 38-53 galectin 1 Homo sapiens 13-18 24231767-9 2014 Segregation of Lck and Gal-1 induced apoptosis was diminished in T-cells with low GM1 expression compared to T-cells with high GM1. G(M1) Ganglioside 82-85 galectin 1 Homo sapiens 23-28 24231767-9 2014 Segregation of Lck and Gal-1 induced apoptosis was diminished in T-cells with low GM1 expression compared to T-cells with high GM1. G(M1) Ganglioside 127-130 galectin 1 Homo sapiens 23-28 24231767-10 2014 Our results show that spatial regulation of Lck by CD45 and GM1 ganglioside determines the outcome of apoptotic response to Gal-1 and this local regulation may occur only upon intimate effector (Gal-1 expressing) cell-T-cell attachment. G(M1) Ganglioside 60-75 galectin 1 Homo sapiens 124-129 22289946-0 2012 Intravenous immunoglobulin treatment on anti-GM1 antibodies associated neuropathies inhibits cholera toxin and galectin-1 binding to ganglioside GM1. G(M1) Ganglioside 45-48 galectin 1 Homo sapiens 111-121 22289946-0 2012 Intravenous immunoglobulin treatment on anti-GM1 antibodies associated neuropathies inhibits cholera toxin and galectin-1 binding to ganglioside GM1. G(M1) Ganglioside 145-148 galectin 1 Homo sapiens 111-121 22289946-5 2012 In this observation, we have the result different from the hypothesis of presence of anti-idiotypic antibodies in different IVIg preparations, and show that IVIg inhibits the binding of cholera toxin and galectin-1 to GM1-expressing cells using flow cytometry. G(M1) Ganglioside 218-221 galectin 1 Homo sapiens 204-214 18581052-6 2008 Based on their strong intracellular co-localization, two glycoconjugates, GM1 ganglioside and CD7 are implicated in the sorting of internalized Gal-1 into Golgi. G(M1) Ganglioside 74-89 galectin 1 Homo sapiens 144-149 16497300-5 2006 Galectin-1 is a member of an adhesion/growth-regulatory family known to interact for example with ganglioside GM(1) and also the hydrophobic tail of oncogenic H-Ras. G(M1) Ganglioside 110-115 galectin 1 Homo sapiens 0-10 14674750-0 2003 Unique conformer selection of human growth-regulatory lectin galectin-1 for ganglioside GM1 versus bacterial toxins. G(M1) Ganglioside 76-91 galectin 1 Homo sapiens 61-71 14674750-3 2003 Using the growth-regulatory interaction of the pentasaccharide of ganglioside GM(1) with homodimeric galectin-1 on neuroblastoma cell surfaces as a model, we present a suitable strategy for addressing this issue. G(M1) Ganglioside 78-83 galectin 1 Homo sapiens 101-111