PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34209843-1 2021 In the search for new chemical scaffolds able to afford NLRP3 inflammasome inhibitors, we used a pharmacophore-hybridization strategy by combining the structure of the acrylic acid derivative INF39 with the 1-(piperidin-4-yl)1,3-dihydro-2H-benzo(d)imidazole-2-one substructure present in HS203873, a recently identified NLRP3 binder. 1-(piperidin-4-yl)1,3-dihydro-2h-benzo(d)imidazole-2-one 207-263 NLR family pyrin domain containing 3 Homo sapiens 56-61 34209843-1 2021 In the search for new chemical scaffolds able to afford NLRP3 inflammasome inhibitors, we used a pharmacophore-hybridization strategy by combining the structure of the acrylic acid derivative INF39 with the 1-(piperidin-4-yl)1,3-dihydro-2H-benzo(d)imidazole-2-one substructure present in HS203873, a recently identified NLRP3 binder. 1-(piperidin-4-yl)1,3-dihydro-2h-benzo(d)imidazole-2-one 207-263 NLR family pyrin domain containing 3 Homo sapiens 320-325