PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27057358-5 2016 Here we found that overexpression of chondroitin 6-sulfotransferase-1 (C6ST-1), which catalyzes 6-sulfation of CS chains, selectively decreased aggrecan, a major CSPG in PNNs, in the aged brain without affecting other PNN components. Chondroitin Sulfates 111-113 carbohydrate sulfotransferase 3 Homo sapiens 37-69 27057358-5 2016 Here we found that overexpression of chondroitin 6-sulfotransferase-1 (C6ST-1), which catalyzes 6-sulfation of CS chains, selectively decreased aggrecan, a major CSPG in PNNs, in the aged brain without affecting other PNN components. Chondroitin Sulfates 111-113 carbohydrate sulfotransferase 3 Homo sapiens 71-77 27057358-7 2016 C6ST-1 increased 6-sulfation in both the repeating disaccharide region and linkage region of CS chains. Chondroitin Sulfates 93-95 carbohydrate sulfotransferase 3 Homo sapiens 0-6 23129769-4 2012 Reactions with chondroitin polymerase generated non-sulfated chondroitin, and those with C4ST-1 and C6ST-1 generated uniformly sulfated CS containing >95% 4S and 6S units, respectively. Chondroitin Sulfates 136-138 carbohydrate sulfotransferase 3 Homo sapiens 100-106 15215498-4 2004 C6ST-1 catalyzes the modifying step of chondroitin sulfate (CS) synthesis by transferring sulfate to the C-6 position of the N-acetylgalactosamine of chondroitin. Chondroitin Sulfates 39-58 carbohydrate sulfotransferase 3 Homo sapiens 0-6 15215498-4 2004 C6ST-1 catalyzes the modifying step of chondroitin sulfate (CS) synthesis by transferring sulfate to the C-6 position of the N-acetylgalactosamine of chondroitin. Chondroitin Sulfates 60-62 carbohydrate sulfotransferase 3 Homo sapiens 0-6 15215498-9 2004 Our results indicate that the mutation in CHST3 described here causes a specific but generalized defect of CS chain sulfation resulting in chondrodysplasia with major involvement of the spine. Chondroitin Sulfates 107-109 carbohydrate sulfotransferase 3 Homo sapiens 42-47 32315540-2 2020 Inflammation and fibrosis are important processes in liver responses to injury and it has been suggested that they and dual ERA-induced liver injury are mediated by the proteoglycan component chondroitin sulfate (CS), which is synthesized by CHST3 and CHST13. Chondroitin Sulfates 192-211 carbohydrate sulfotransferase 3 Homo sapiens 242-247 32315540-2 2020 Inflammation and fibrosis are important processes in liver responses to injury and it has been suggested that they and dual ERA-induced liver injury are mediated by the proteoglycan component chondroitin sulfate (CS), which is synthesized by CHST3 and CHST13. Chondroitin Sulfates 213-215 carbohydrate sulfotransferase 3 Homo sapiens 242-247 27753269-3 2017 CHST3 gene encodes the enzyme chondroitin 6-O-sulfotransferase-1 (C6ST-1) which mediates the sulfation of proteoglycans, (chondroitin sulfate), in the extracellular matrix of cartilage. Chondroitin Sulfates 122-141 carbohydrate sulfotransferase 3 Homo sapiens 0-5 27753269-3 2017 CHST3 gene encodes the enzyme chondroitin 6-O-sulfotransferase-1 (C6ST-1) which mediates the sulfation of proteoglycans, (chondroitin sulfate), in the extracellular matrix of cartilage. Chondroitin Sulfates 122-141 carbohydrate sulfotransferase 3 Homo sapiens 30-64 27753269-3 2017 CHST3 gene encodes the enzyme chondroitin 6-O-sulfotransferase-1 (C6ST-1) which mediates the sulfation of proteoglycans, (chondroitin sulfate), in the extracellular matrix of cartilage. Chondroitin Sulfates 122-141 carbohydrate sulfotransferase 3 Homo sapiens 66-72 23696150-5 2013 It was found that both CHST3 and CHST15 have higher activities at the non-reducing end (NRE) units of chondroitin sulfate, particularly those terminating with a GalNAc monosaccharide. Chondroitin Sulfates 102-121 carbohydrate sulfotransferase 3 Homo sapiens 23-28 9639683-1 1998 Chondroitin 6-sulfotransferase (C6ST) is the key enzyme in the biosynthesis of chondroitin 6-sulfate, a glycosaminoglycan implicated in chondrogenesis, neoplasia, atherosclerosis, and other processes. Chondroitin Sulfates 79-100 carbohydrate sulfotransferase 3 Homo sapiens 0-30 9639683-1 1998 Chondroitin 6-sulfotransferase (C6ST) is the key enzyme in the biosynthesis of chondroitin 6-sulfate, a glycosaminoglycan implicated in chondrogenesis, neoplasia, atherosclerosis, and other processes. Chondroitin Sulfates 79-100 carbohydrate sulfotransferase 3 Homo sapiens 32-36 34966741-5 2021 In the human placenta, where the distinct chondroitin sulfate is specifically bound with VAR2CSA on Plasmodium parasite-infected RBC, eight chondroitin sulfate biosynthesis enzymes (CSGALNACT1, CSGALNACT2, CHSY3, CHSY1, CHPF, DSE, CHST11, and CHST3) were significantly higher than the normal colon tissue. Chondroitin Sulfates 42-61 carbohydrate sulfotransferase 3 Homo sapiens 243-248