PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2661062-11	1989	The present data indicate that: (i) the expression of M/TPO-AG in human thyroid cells is dependent on TSH stimulation, through pathways which involve cAMP production and protein synthesis, (ii) TSAb reproduces this effect of TSH; (iii) oestradiol and NaI have no direct influence on the expression of M/TPO-Ag.	Sodium Iodide	251-254	thyroid peroxidase	Homo sapiens	56-59	
1518372-5	1992	Thyroid peroxidase (TPO) activity in the cultured follicles with TSH for 96 h was dose-dependently inhibited by NaI.	Sodium Iodide	112-115	thyroid peroxidase	Homo sapiens	0-18	
1518372-5	1992	Thyroid peroxidase (TPO) activity in the cultured follicles with TSH for 96 h was dose-dependently inhibited by NaI.	Sodium Iodide	112-115	thyroid peroxidase	Homo sapiens	20-23	
1518372-6	1992	One hundred microM of NaI completely inhibited TSH-induced TPO activity.	Sodium Iodide	22-25	thyroid peroxidase	Homo sapiens	59-62	
1518372-9	1992	These data provide direct evidences that thyroid hormone synthesis is regulated by NaI as well as TSH at least in part via regulation of TPO activity and also that both EGF and PMA are inhibitory on thyroid hormone formation.	Sodium Iodide	83-86	thyroid peroxidase	Homo sapiens	137-140	
2090100-3	1990	Purified porcine thyroglobulin or bovine serum albumin as acceptor protein was iodinated with [125I]NaI and H2O2 by purified porcine TPO.	Sodium Iodide	100-103	thyroid peroxidase	Homo sapiens	133-136	
14976143-8	2004	In an attempt to determine the mechanism by which these gene expressions occurred, we detected the inhibition of protein synthesis by cycloheximide, which up-regulated the expression of thyroperoxidase and thyroglobulin mRNA in HDACI-treated cells and down-regulated that of sodium/iodide symporter mRNA.	Sodium Iodide	275-288	thyroid peroxidase	Homo sapiens	186-201	
26253711-2	2016	Thyroid and breast tissues both express the sodium iodide symporter (NIS), similarly both have a peroxidase activity, TPO and lactoperoxidase (LPO) respectively.	Sodium Iodide	44-57	thyroid peroxidase	Homo sapiens	118-121	
22498723-1	2012	Cotransfer of thyroid-specific transcription factor (TTF)-1 and Pax-8 gene to tumor cells, resulting in the re-expression of iodide metabolism-associated proteins, such as sodium iodide symporter (NIS), thyroglobulin (Tg), thyroperoxidase (TPO), offers the possibility of radioiodine therapy to non-iodide-concentrating tumor because the expression of iodide metabolism-associated proteins in thyroid are mediated by the thyroid transcription factor TTF-1 and Pax-8.	Sodium Iodide	172-185	thyroid peroxidase	Homo sapiens	223-238	
22498723-1	2012	Cotransfer of thyroid-specific transcription factor (TTF)-1 and Pax-8 gene to tumor cells, resulting in the re-expression of iodide metabolism-associated proteins, such as sodium iodide symporter (NIS), thyroglobulin (Tg), thyroperoxidase (TPO), offers the possibility of radioiodine therapy to non-iodide-concentrating tumor because the expression of iodide metabolism-associated proteins in thyroid are mediated by the thyroid transcription factor TTF-1 and Pax-8.	Sodium Iodide	172-185	thyroid peroxidase	Homo sapiens	240-243	
11571539-0	2001	Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer.	Sodium Iodide	105-118	thyroid peroxidase	Homo sapiens	26-41