PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31967940-4 2020 The depletion of SPOP or overexpression of a prostate cancer-associated SPOP mutant, F133V, in androgen receptor-positive prostate cancer cells increased the amount of topoisomerase 2A (TOP2A) in the nuclei together with the increased amount of gammaH2AX, an indication of DNA breaks. Androgens 95-103 DNA topoisomerase II alpha Homo sapiens 168-184 31967940-4 2020 The depletion of SPOP or overexpression of a prostate cancer-associated SPOP mutant, F133V, in androgen receptor-positive prostate cancer cells increased the amount of topoisomerase 2A (TOP2A) in the nuclei together with the increased amount of gammaH2AX, an indication of DNA breaks. Androgens 95-103 DNA topoisomerase II alpha Homo sapiens 186-191