PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31836808-0 2019 hASH1 nuclear localization persists in neuroendocrine transdifferentiated prostate cancer cells, even upon reintroduction of androgen. Androgens 125-133 achaete-scute family bHLH transcription factor 1 Homo sapiens 0-5 31836808-2 2019 Cell fate regulator ASCL1/hASH1"s expression was markedly induced in androgen deprived (AD) LNCaP cells and prominent nuclear localisation accompanied acquisition of the NE-like morphology and expression of NE markers (NSE). Androgens 69-77 achaete-scute family bHLH transcription factor 1 Homo sapiens 20-25 31836808-2 2019 Cell fate regulator ASCL1/hASH1"s expression was markedly induced in androgen deprived (AD) LNCaP cells and prominent nuclear localisation accompanied acquisition of the NE-like morphology and expression of NE markers (NSE). Androgens 69-77 achaete-scute family bHLH transcription factor 1 Homo sapiens 26-31 31836808-3 2019 By contrast, androgen-insensitive PC3 and DU145 cells displayed clear nuclear hASH1 localisation under control conditions that was unchanged by AD, suggesting AR signalling negatively regulated hASH1 expression and localisation. Androgens 13-21 achaete-scute family bHLH transcription factor 1 Homo sapiens 78-83 31836808-3 2019 By contrast, androgen-insensitive PC3 and DU145 cells displayed clear nuclear hASH1 localisation under control conditions that was unchanged by AD, suggesting AR signalling negatively regulated hASH1 expression and localisation. Androgens 13-21 achaete-scute family bHLH transcription factor 1 Homo sapiens 194-199 31836808-4 2019 Synthetic androgen (R1881) prevented NE transdifferentiation of AD LNCaP cells and markedly suppressed expression of key regulators of lineage commitment and neurogenesis (REST and ASCL1/hASH1). Androgens 10-18 achaete-scute family bHLH transcription factor 1 Homo sapiens 181-186 31836808-4 2019 Synthetic androgen (R1881) prevented NE transdifferentiation of AD LNCaP cells and markedly suppressed expression of key regulators of lineage commitment and neurogenesis (REST and ASCL1/hASH1). Androgens 10-18 achaete-scute family bHLH transcription factor 1 Homo sapiens 187-192