PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31620371-8 2019 Among the six ECM genes, SPP1 was identified as the key hub signature for PCa metastasis and drug resistance development; we found that both protein and mRNA expression levels of SPP1 were remarkably up-regulated in mCRPC compared with HSPC in organoid models and could regulate the androgen receptor signaling pathway. Androgens 283-291 secreted phosphoprotein 1 Homo sapiens 179-183