PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18279803-7	2008	Fisetin also inhibited the gene expression of TNF-alpha, interleukin (IL)-1 beta, cyclooxygenase (COX-2) and inducible nitric oxide synthase (iNOS) at both mRNA and protein levels.	fisetin	0-7	interleukin 1 beta	Mus musculus	57-80	
28213268-10	2017	We found that fisetin inhibited IL-1beta-induced expression of NO, PGE2, TNF-alpha, IL-6, COX-2, iNOS, MMP-3, MMP-13, ADAMTS-5.	fisetin	14-21	interleukin 1 beta	Mus musculus	32-40	
28213268-12	2017	Furthermore, fisetin significantly inhibited IL-1beta-induced SIRT1 decrease and inactivation.	fisetin	13-20	interleukin 1 beta	Mus musculus	45-53	
27209403-8	2016	Further neurochemical assays suggested that pretreatment with fisetin reversed LPS-induced overexpression of pro-inflammatory cytokine (IL-1beta, IL-6 and TNF-alpha) in the hippocampus and the prefrontal cortex (PFC).	fisetin	62-69	interleukin 1 beta	Mus musculus	136-144	
26878795-5	2016	Moreover, fisetin reduced the levels of myeloperoxidase activity, the production of proinflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1beta) and interleukin-6 (IL-6) and the expressions of COX-2 and iNOS in the colon tissues.	fisetin	10-17	interleukin 1 beta	Mus musculus	152-170	
26878795-5	2016	Moreover, fisetin reduced the levels of myeloperoxidase activity, the production of proinflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1beta) and interleukin-6 (IL-6) and the expressions of COX-2 and iNOS in the colon tissues.	fisetin	10-17	interleukin 1 beta	Mus musculus	172-180	
31207963-9	2019	Moreover, fisetin treatment inhibited LPS-induced activation of the inflammatory Toll-like Receptors (TLR4)/cluster of differentiation 14 (CD14)/phospho-nuclear factor kappa (NF-kappaB) signaling and attenuated other inflammatory mediators (tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL1-beta), and cyclooxygenase (COX-2).	fisetin	10-17	interleukin 1 beta	Mus musculus	282-300	
31207963-9	2019	Moreover, fisetin treatment inhibited LPS-induced activation of the inflammatory Toll-like Receptors (TLR4)/cluster of differentiation 14 (CD14)/phospho-nuclear factor kappa (NF-kappaB) signaling and attenuated other inflammatory mediators (tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL1-beta), and cyclooxygenase (COX-2).	fisetin	10-17	interleukin 1 beta	Mus musculus	302-310