PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29296070-0 2017 Fisetin inhibits epidermal growth factor-induced migration of ARPE-19 cells by suppression of AKT activation and Sp1-dependent MMP-9 expression. fisetin 0-7 epidermal growth factor Homo sapiens 17-40 29296070-6 2017 Results: Fisetin did not affect ARPE-19 cell viability and significantly inhibited the EGF-induced migration capacity of ARPE-19 cells. fisetin 9-16 epidermal growth factor Homo sapiens 87-90 29296070-9 2017 Fisetin combined with LY294002 (an inhibitor of AKT) prevented the EGF-induced migration involved in downregulation of Sp1 and MMP-9 expression. fisetin 0-7 epidermal growth factor Homo sapiens 67-70 29296070-11 2017 Conclusions: Fisetin inhibited EGF-induced cell migration via modulation of AKT/Sp1-dependent MMP-9 transcriptional activity. fisetin 13-20 epidermal growth factor Homo sapiens 31-34 29296070-2 2017 Fisetin is a naturally occurring compound that has been reported to have antitumor effects, but its effects on epidermal growth factor (EGF)-induced cell migration and the underlying mechanisms remain unclear. fisetin 0-7 epidermal growth factor Homo sapiens 111-134 29296070-2 2017 Fisetin is a naturally occurring compound that has been reported to have antitumor effects, but its effects on epidermal growth factor (EGF)-induced cell migration and the underlying mechanisms remain unclear. fisetin 0-7 epidermal growth factor Homo sapiens 136-139 29296070-3 2017 Methods: Effects of fisetin on EGF-induced cell viability and migration were examined with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and in vitro migration assays. fisetin 20-27 epidermal growth factor Homo sapiens 31-34