PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34173812-8 2021 Fisetin could also ameliorate and reduce oxLDL-induced upregulation of SREBP-1 and thereby expression of its downstream liposynthesis genes HMGCR and FAS via inhibiting ROS-induced NLRP3 activation. fisetin 0-7 fatty acid synthase Homo sapiens 150-153 34173812-9 2021 In conclusion, fisetin could inhibit foam cell formation by blocking oxLDL induced ROS formation and subsequent NLRP3 activation, thereby inhibiting SREBP-1 and its downstream genes including FAS and HMGCR. fisetin 15-22 fatty acid synthase Homo sapiens 192-195