PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32051749-0 2020 Fisetin regulates gut microbiota to decrease CCR9+/CXCR3+/CD4+ T-lymphocyte count and IL-12 secretion to alleviate premature ovarian failure in mice. fisetin 0-7 chemokine (C-X-C motif) receptor 3 Mus musculus 51-56 32051749-6 2020 Finally, flow cytometry analysis showed that the numbers of CCR9+/CXCR3+/CD4+ T lymphocytes in the peripheral blood of POF mice in the fisetin group were significantly reduced, along with the number of CD4+/interleukin (IL)-12+ cells. fisetin 135-142 chemokine (C-X-C motif) receptor 3 Mus musculus 66-71 32051749-7 2020 Therefore, our data suggested that fisetin regulates the distribution and bacterial counts of Akkermansia and uncultured_bacterium_f_Lachnospiracea in POF mice, and reduces peripheral blood CCR9+/CXCR3+/CD4+ T-lymphocyte count and IL-12 secretion to regulate the ovarian microenvironment and reduce inflammation, thus exerting therapeutic effects against POF. fisetin 35-42 chemokine (C-X-C motif) receptor 3 Mus musculus 196-201