PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19321592-7	2009	Preincubation with fisetin and tricetin strongly attenuated LPS-induced increases in concentrations of TNFalpha in blood from COPD patients [mean (+/- SEM): -41 +/- 4% (fisetin) and -31 +/- 4% (tricetin); P < 0.001] and IL-6 in blood from T2D patients [-31 +/- 5% (fisetin) and -29 +/- 6% (tricetin); P < or = 0.001].	fisetin	19-26	interleukin 6	Homo sapiens	223-227	
19321592-8	2009	Moreover, LPS-induced changes in TNFalpha and IL-6 concentrations were positively correlated with the extent of reduction by fisetin and tricetin.	fisetin	125-132	interleukin 6	Homo sapiens	46-50	
29758489-4	2018	Fisetin significantly inhibited COX-2 expression and reduced prostaglandin E2 production, and it suppressed the levels of IL-8, CCL5, monocyte chemotactic protein 1, tumor necrosis factor alpha, and IL-6.	fisetin	0-7	interleukin 6	Homo sapiens	199-203	
26590114-7	2015	Fisetin also inhibited the production of NO, PGE2 IL-1beta, IL-6, expression of iNOS and COX-2, and activation of NF-kappaB in HaCaT cells treated with TNF-alpha.	fisetin	0-7	interleukin 6	Homo sapiens	60-64	
23320034-7	2012	Fisetin was added (3-10 muM) for 48 h. While the HG condition significantly induced histone acetylation, NF-kappaB activation, and proinflammatory cytokine (IL-6 and TNF-alpha) release from THP-1 cells, fisetin suppressed NF-kappaB activity and cytokine release.	fisetin	0-7	interleukin 6	Homo sapiens	157-161	
17079162-4	2007	Fisetin decreased phorbol-12-myristate 13-acetate plus calcium ionophore A23187 (PMACI)-stimulated gene expression and production of tumor necrosis factor-alpha (TNF-alpha), interleukin (IL)-1beta, IL-4, IL-6, and IL-8 in HMC-1 cells.	fisetin	0-7	interleukin 6	Homo sapiens	204-208