PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25016296-10	2014	Fisetin treatment to 2-D melanoma cultures resulted in phosphorylation and activation of the multifunctional AMP-activated protein kinase (AMPK) involved in the regulation of diverse cellular processes, including autophagy and apoptosis.	fisetin	0-7	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	109-137	
33086879-0	2021	Fisetin Inhibits Autophagy in HepG2 Cells via PI3K/Akt/mTOR and AMPK Pathway.	fisetin	0-7	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	64-68	
33086879-7	2021	In the Western blotting analysis, fisetin treatment inhibited the expression of Atg7, Atg16L, mTOR, and pACC and elevated the expression of Atg5, AMPKalpha, AMPKbeta1/2, ACC and Akt.	fisetin	34-41	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	157-168	
33086879-8	2021	Taken together, the results revealed that fisetin inhibited autophagy by the activation of PI3K/Akt/mTOR and modulation of AMPK signaling pathways.	fisetin	42-49	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	123-127	
25016296-10	2014	Fisetin treatment to 2-D melanoma cultures resulted in phosphorylation and activation of the multifunctional AMP-activated protein kinase (AMPK) involved in the regulation of diverse cellular processes, including autophagy and apoptosis.	fisetin	0-7	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	139-143	
25016296-11	2014	Silencing of AMPK failed to prevent cell death indicating that fisetin induced cytotoxicity is mediated through both AMPK-dependent and -independent mechanisms.	fisetin	63-70	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	117-121