PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10996483-4	2000	Compared to control incubations (no inhibitor) where cholinesterase activity was inhibited to between 1 and 4% of control levels, incorporation of the CYP2D6 inhibitor quinidine into the microsomal incubation resulted in cholinesterase activity of 50% for parathion, 38% for diazinon and 30% for chlorpyrifos.	Quinidine	168-177	butyrylcholinesterase	Homo sapiens	53-67	
18072155-11	2007	Following in vitro inhibition of pseudo cholinesterase by quinidine sulfate, true cholinesterase activity was estimated in the plasma of the subjects.	Quinidine	58-75	butyrylcholinesterase	Homo sapiens	40-54	
18072155-15	2007	Ten minutes after in vitro addition of quinidine sulfate to inhibit pseudo cholinesterase activity in the plasma, the estimated true cholinesterase activities in males and females were 0.08 and 0.07 DeltapH/20 min, respectively.	Quinidine	39-56	butyrylcholinesterase	Homo sapiens	75-89	
18072155-15	2007	Ten minutes after in vitro addition of quinidine sulfate to inhibit pseudo cholinesterase activity in the plasma, the estimated true cholinesterase activities in males and females were 0.08 and 0.07 DeltapH/20 min, respectively.	Quinidine	39-56	butyrylcholinesterase	Homo sapiens	133-147	
10996483-4	2000	Compared to control incubations (no inhibitor) where cholinesterase activity was inhibited to between 1 and 4% of control levels, incorporation of the CYP2D6 inhibitor quinidine into the microsomal incubation resulted in cholinesterase activity of 50% for parathion, 38% for diazinon and 30% for chlorpyrifos.	Quinidine	168-177	butyrylcholinesterase	Homo sapiens	221-235	
10365641-5	1999	There was a marked decrease in the serum cholinesterase (CHE) activity as QUINID concentrations were increased to 154 micromol/L (19.8% decrease in CHE) and to 308 micromol/L (36.8% decrease in CHE).	Quinidine	74-80	butyrylcholinesterase	Homo sapiens	41-55	
10365641-5	1999	There was a marked decrease in the serum cholinesterase (CHE) activity as QUINID concentrations were increased to 154 micromol/L (19.8% decrease in CHE) and to 308 micromol/L (36.8% decrease in CHE).	Quinidine	74-80	butyrylcholinesterase	Homo sapiens	57-60	
10365641-6	1999	These data suggest that QUINID inhibits the hydrolysis of CE in human serum by suppressing CHE activity.	Quinidine	24-30	butyrylcholinesterase	Homo sapiens	91-94	
10365641-8	1999	They also have important implications for individuals receiving QUINID together with other drugs whose hydrolysis may be catalyzed by CHE.	Quinidine	64-70	butyrylcholinesterase	Homo sapiens	134-137	
2240575-5	1990	In this work, OH-, H+, and quinidine have been used to stop the enzymes LDH (EC 1.1.1.27) (with H+ and OH-) and cholinesterase (EC 3.1.1.8) (with quinidine).	Quinidine	27-36	butyrylcholinesterase	Homo sapiens	96-126	
3674164-0	1987	Inhibitory effect of quinidine on plasma pseudocholinesterase activity in pregnant women.	Quinidine	21-30	butyrylcholinesterase	Homo sapiens	41-61	
3674164-1	1987	The effect of quinidine at therapeutic and subtherapeutic concentrations on pseudocholinesterase activity in the plasma of 16 normal pregnant women was studied.	Quinidine	14-23	butyrylcholinesterase	Homo sapiens	76-96	
3674164-2	1987	The mean plasma pseudocholinesterase activity in the absence of quinidine (control) was 0.67 +/- 0.11 U/ml.	Quinidine	64-73	butyrylcholinesterase	Homo sapiens	16-36	
3674164-3	1987	The mean pseudocholinesterase activity in the presence of quinidine at concentrations of 0.5, 1.0, 2.0, and 5.0 micrograms/ml 0.48 +/- 0.09, 0.38 +/- 0.09, 0.29 +/- 0.10, and 0.19 +/- 0.09 U/ml, respectively.	Quinidine	58-67	butyrylcholinesterase	Homo sapiens	9-29	
3674164-4	1987	At therapeutic concentrations needed to treat cardiac arrhythmias (2 to 5 micrograms/ml), quinidine inhibited pseudocholinesterase activity by 60% to 70%.	Quinidine	90-99	butyrylcholinesterase	Homo sapiens	110-130	
2240575-5	1990	In this work, OH-, H+, and quinidine have been used to stop the enzymes LDH (EC 1.1.1.27) (with H+ and OH-) and cholinesterase (EC 3.1.1.8) (with quinidine).	Quinidine	146-155	butyrylcholinesterase	Homo sapiens	96-126	
3767290-4	1986	We adapted the same technique for the determination of erythrocyte cholinesterase using whole blood as sample and quinidine sulphate as inhibitor of pseudocholinesterase.	Quinidine	114-132	butyrylcholinesterase	Homo sapiens	149-169	
7237776-2	1981	Quinidine sulfate is used as an inhibitor of plasma cholinesterase during the measurement of erythrocyte acetylcholinesterase activity, obviating the need for washing the erythrocytes before lysis.	Quinidine	0-17	butyrylcholinesterase	Homo sapiens	52-66