PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8806763-14	1996	Quinidine, a specific inhibitor of P450 2D6, was not an effective inhibitor of NNK metabolism.	Quinidine	0-9	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	35-39	
10821163-3	2000	The results indicate that sulphaphenazole, quinidine and alpha-naphthoflavone are selective inhibitors of CYP2C9 (IC50 = 0.5-0.7 microM), CYP2D6 (0.3-0.4 microM) and CYP1A (0.05-5 microM) respectively on the basis of the IC50, which are much lower than those of other P450 isoforms (> 10-fold).	Quinidine	43-52	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	268-272	
21105702-3	2010	The electrochemical response of the P450-electrode in the microfluidic cell was tested using four drugs that are known substrates of P450 3A4: quinidine, nifedipine, alosetron and ondansetron.	Quinidine	143-152	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	36-40	
7890608-5	1995	The rate of CO binding to the total mixture of P450 3A4 conformers was increased in the presence of nifedipine and erythromycin, decreased by quinidine, testosterone, and warfarin, and unaffected by cimetidine and 17 alpha-ethynylestradiol.	Quinidine	142-151	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	47-51	
7935340-7	1994	However, at low substrate concentrations bufuralol 1"-hydroxylation was shown to be catalyzed principally by P450 2D6, based on the inhibitory effects of anti-rat P450 2D1 antibody and quinidine, in both human samples HL-18 and HL-67.	Quinidine	185-194	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	109-113	
2263067-10	1990	These data show that quinidine inhibits in vivo metabolism of amphetamine in rats and suggest that amphetamine metabolism may, in part, be mediated by an isozyme of P450 which displays genetic polymorphism.	Quinidine	21-30	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	165-169	
2306418-4	1990	Otherwise, no significant phenotypic differences in total or metabolic clearance were found and it is concluded that the metabolism of quinidine is largely carried out by P450 isoenzymes different from P450db1.	Quinidine	135-144	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	171-175	
21336516-7	2011	The most selective inhibitors available are furafylline (in co-incubation and pre-incubation conditions) for CYP1A2, 2-phenyl-2-(1-piperidinyl)propane (PPP) for CYP2B6, montelukast for CYP2C8, sulfaphenazole for CYP2C9, (-)-N-3-benzyl-phenobarbital for CYP2C19 and quinidine for CYP2D6.	Quinidine	265-274	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	161-167