PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8250956-0 1993 Effect of alpha 1-acidglycoprotein on myocardial uptake and pharmacodynamics of quinidine in perfused rat heart. Quinidine 80-89 orosomucoid 1 Rattus norvegicus 10-34 8250956-3 1993 The equilibration rate constant for the quinidine output concentration increased with increasing AAG concentration, but not as much as predicted by the conventional pharmacokinetic uptake model, which assumes constant capillary permeability among the phases. Quinidine 40-49 orosomucoid 1 Rattus norvegicus 97-100 2713218-0 1989 Lack of effect of treatment with human recombinant-tumour necrosis factor (HrTNF) on the binding of quinidine to alpha 1-acid glycoprotein (AGP). Quinidine 100-109 orosomucoid 1 Rattus norvegicus 140-143 2713218-4 1989 It was observed that the quinidine binding ratio (the quotient of bound and free concentration in plasma) was highly correlated with the plasma concentration of AGP (r = 0.818) and that the mean pretreatment AGP concentration in the patients was about three times that found in normal subjects. Quinidine 25-34 orosomucoid 1 Rattus norvegicus 161-164 2713218-4 1989 It was observed that the quinidine binding ratio (the quotient of bound and free concentration in plasma) was highly correlated with the plasma concentration of AGP (r = 0.818) and that the mean pretreatment AGP concentration in the patients was about three times that found in normal subjects. Quinidine 25-34 orosomucoid 1 Rattus norvegicus 208-211