PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11765139-0	2001	Differential inhibition of human CYP1A1 and CYP1A2 by quinidine and quinine.	Quinidine	54-63	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	44-50	
11765139-2	2001	The inhibition of recombinant CYP1A1 and CYP1A2 activity by quinidine and quinine was evluated using ethoxyresorutin O-deethylation, phenacetin O-deethylation and propranolol desisopropylation as probe catalytic pathways.	Quinidine	60-69	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	41-47	
10492058-1	1999	OBJECTIVE: To investigate the possible involvement of cytochromes CYP1A2 and CYP2C19 in the in vivo oxidative metabolism of quinidine.	Quinidine	124-133	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	66-72	
10078840-6	1999	Furafylline, sulphaphenazole, omeprazole, quinidine and ketoconazole were identified as specific markers for the respective CYP1A2 (IC50 = 6 microM), CYP2C9 (0.7 microM), CYP2C19 (6 microM), CYP2D6 (0.02 microM) and CYP3A4 (0.2 microM) inhibition screens.	Quinidine	42-51	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	124-130	
10418968-11	1999	Furafylline, sulfaphenazole, quinidine, and ketoconazole were found to be specific inhibitors of CYP1A2, CYP2C9, CYP2D6, and CYP3A4, respectively.	Quinidine	29-38	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	97-103	
8591723-4	1995	Studies with human hepatic microsomes and the specific inhibitors furafylene, quinidine, and ketoconazole confirmed the role of CYP1A2 and CYP2D6 and also demonstrated the involvement of the CYP3A subfamily.	Quinidine	78-87	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	128-134	
35246464-5	2022	The current study also demonstrated that selective inhibition sufficient for fm calculation was achieved by inhibitors of CYP1A2 (20 microM furafylline), CYP2C8 (40 microM montelukast), CYP2C9 (40 microM sulfaphenazole), CYP2C19 (3 microM (-)N-3-benzyl-phenobarbital) and CYP2D6 (5 microM quinidine).	Quinidine	289-298	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	122-128	
31147315-5	2019	Using the differential inhibition of the human enzymes by quinidine, we developed a method to distinguish the relative contribution of CYP1A1 or CYP1A2 in the metabolism of drugs and foreign compounds.	Quinidine	58-67	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	145-151	
22266842-7	2012	Furafylline, quinidine, and ketoconazole, selective inhibitors of CYP1A2, CYP2D6, and CYP3A4, respectively, inhibited 5-hydroxylorcaserin (IC(50) = 1.914 muM), 7-hydroxylorcaserin (IC(50) = 0.213 muM), and 1-hydroxylorcaserin formation (IC(50) = 0.281 muM), respectively.	Quinidine	13-22	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	66-72	
20924570-3	2010	Enzyme activities of CYP1A2 and CYP3A4 were determined as metabolic ratios of caffeine (CMR = (AFMU + 1MU + 1MX)/17DMU) and quinidine (QMR = 3-hydroxy-quinidine/quinidine) respectively before and 34 h after insertion of the suppository.	Quinidine	124-133	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	21-27	
20924570-3	2010	Enzyme activities of CYP1A2 and CYP3A4 were determined as metabolic ratios of caffeine (CMR = (AFMU + 1MU + 1MX)/17DMU) and quinidine (QMR = 3-hydroxy-quinidine/quinidine) respectively before and 34 h after insertion of the suppository.	Quinidine	151-160	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	21-27